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Transcriptomic analysis of human laryngeal carcinoma cell line LIU-LSC-1 with depletion of ITGA5

ABSTRACT: Transcriptomic analysis of human laryngeal carcinoma cell line LIU-LSC-1 with depletion of ITGA5

PROVIDER: PRJNA746775 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR15146506_1.fastq.gz	Fastqsanger.gz
	SRR15146506_2.fastq.gz	Fastqsanger.gz
	SRR15146507_1.fastq.gz	Fastqsanger.gz
	SRR15146507_2.fastq.gz	Fastqsanger.gz
	SRR15146508_1.fastq.gz	Fastqsanger.gz

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Transcriptomic analysis of human laryngeal carcinoma cell line LIU-LSC-1 with depletion of ITGA5

Project description:Recent studies have shown that integrins have a promotive effect on cancer. In our clinical work, we found that integrin subunit alpha 5 (ITGA5) was highly expressed in laryngeal cancer tissues. Further in vitro functional assays showed that ITGA5 promotes proliferation, migration and metastasis of laryngeal cancer cells. To investigate how ITGA5 exerts these functions and its downstream regulatory genes, we knocked down ITGA5 in the laryngeal cancer cell line LIU-LSC-1 and sequenced the transcriptome of wild-type and ITGA5 knockdown cells.

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Transcriptomic analysis of human laryngeal carcinoma cell line LIU-LSC-1 with depletion of Raptor

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Effect of PFKP deletion on gene expression in laryngeal carcinoma cells LIU-LSC-1

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Effect of PFKP deletion on gene expression in laryngeal carcinoma cells LIU-LSC-1

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Effect of PRMT1 deletion on head and neck squamous cell carcinoma cells LIU-LSC-1

Project description:To investigate the role of PRMT1 in head and neck squamous cell carcinoma, we established a LIU-LSC-1 cell line with PRMT1 knocked down by lentivirus technique. We then performed profiling targeting the ATAC-seq data of the control and PRMT1 knockdown groups

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Effect of PRMT1 deletion on gene expression in head and neck squamous cell carcinoma cells LIU-LSC-1

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Effect of PRMT1 deletion on gene expression in head and neck squamous cell carcinoma cells LIU-LSC-1

Project description:Effect of PRMT1 deletion on gene expression in head and neck squamous cell carcinoma cells LIU-LSC-1

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