Ontology highlight
ABSTRACT:
PROVIDER: PRJNA756137 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Salvia miltiorrhiza Bunge;TCM
Danshen POS NEG IDA; SCIEX ZenoTOF7600;
China,Beijing
2025-03-06 | MSV000097251 | MassIVE
Project description:Atractylodes macrocephala is a traditional Chinese medicine in China. It is widely used in clinic and the market demand is great. The quality difference between A. chinensis(Bunge) Koidz and A. japonica Koidz.ex Kitam is great, which seriously affects its clinical curative effect. Determination of Atractylosin by High-performance liquid chromatography. Transcriptomics coupled with Metabonomics for elucidating differences between the components in A. chinensis(Bunge) Koidz and A. japonica Koidz.ex Kitam. It was found that ACS, ACC, PAL and NOS were the key genes and metabolites related to the synthesis of atractylodes macrocephala. The decrease of salicylic acid content in A. chinensis(Bunge) Koidz may lead to the decrease of its ability to mediate the elicitor of endophytic fungi, resulting in the down-regulation of the expression of TGAL4 transcription factor and the up-regulation of DOGL3 transcription factor in A. chinensis(Bunge) Koidz cells, which may affect the accumulation of Atractylosin. The study above provides a theoretical basis for elucidating the biosynthesis pathway of atractylosin in A. chinensis(Bunge) Koidz.
2024-09-28 | GSE278290 | GEO
Project description:Autologous fat grafting (AFG), although an appealing approach to repair soft tissue defects, has various complications. Excessive inflammation at the transplant site is one of the main reasons for the poor effect of fat transplantation and occurrence of complications. Our previous study proved that Salvia miltiorrhiza can enhance fat graft survival. Salvianolic acid B (Sal-B) is the most abundant and bioactive water-soluble compound in Salvia miltiorrhiza and has anti-inflammatory effects on other diseases. Therefore, we hypothesized that salvianolic acid B could improve the effect of fat grafts by inhibiting inflammation.
2023-09-14 | GSE186886 | GEO
Project description:<p>This study used in-situ soil from five different cultivation areas (Beijing, Henan, Sichuan, Shandong, Shaanxi) to plant 4 different varieties of Salvia miltiorrhiza. At the same time, Beijing soil was separately selected for bacterial agent pot experiments. These root exudates were collected at different growth stages of Salvia miltiorrhiza for metabolomics detection and analysis. The effects of different soil types and genotypes mediated root exudates on Salvia miltiorrhiza quality were observed, as well as the effects of different microbial agents mediated root exudates on the active ingredients of Salvia miltiorrhiza.</p>
2025-03-14 | MTBLS11800 | MetaboLights
Project description:To further investigate the potential molecular basis of the therapeutic effects of the mixture of salvianolic acids from Salvia miltiorrhiza and total flavonoids from Anemarrhena asphodeloides (MSTF) on sulfur mustard (SM) damage, gene expression analysis was conducted on rats liver tissues using microarrays.
2014-11-05 | GSE62994 | GEO
Project description:Salvia is an important genus from the Lamiaceae with approximately 1000 species distributed globally. Several Salvia species are commercially important because of their medicinal and culinary properties. We report the construction of the first fingerprinting array for Salvia species enriched with polymorphic and divergent DNA sequences and demonstrate the potential of this array for fingerprinting several economically important members of this genus. In order to generate the Salvia Subtracted Diversity Array (SDA), a Suppression Subtractive Hybridization (SSH) was performed between a pool of ten Salvia species and a pool of non-angiosperm and angiosperms (excluding the Lamiaceae) to selectively isolate Salvia-specific sequences. A total of 285 subtracted genomic DNA (gDNA) fragments were amplified and arrayed. DNA fingerprints were obtained for fifteen Salvia genotypes including three that were not part of the original subtraction pool. Hierarchical cluster analysis indicated that the Salvia-specific SDA was capable of differentiating closely related species of S. officinalis and S. miltiorrhiza and was also able to reveal genetic relationships consistent with geographical origins. Species-specific features were also found for S. elegans, S. officinalis, S. sclarea, S. przewalskii and S. runcinata.
2013-07-31 | E-GEOD-39403 | biostudies-arrayexpress
Project description:Carbon dots (CDs) can affect plant growth and disease resistance and assist siRNA/DNA delivery. Salvia miltiorrhiza-Derived Carbon Dots were recently found to facilitate plants to adapt to environmental stresses through amplifying Ca2+ signaling and scavenging reactive oxygen species (ROS). More importantly, CDs can be degraded into CO2 and H2O within plant cells, thereby having fewer biosafety issues as compared to those undegradable ones and receiving more attentions in the plant community. However, the molecular mechanisms underlying effects of CD priming on plant growth and development have not been well characterized. In this study, we conducted transcriptomic assays and aim to reveal how CD priming affect root development through transcriptional reprogramming in rice.
2025-05-10 | GSE202652 | GEO