Project description:Skin homeostasis is guided by spatiotemporal regulation of gene expression, establishing each stage of keratinocyte differentiation. The current study presents transcriptomic and chromatin profiling for the proliferating (basal) and differentiated (suprabasal) cell populations derived from neonate mice (p0-p2) skin epidermis. This multi-omic approach will enable idenitification of cell specific epidermal cross-talk central to the equlibirum.
Project description:Here, we explored the circRNA expression profiles of adult and neonatal mouse ovaries by high-throughput sequencing. A total of 28,000 circRNAs were identified in adult and neonatal ovaries The results showed that 343 circRNAs were up-regulated and 146 circRNAs were down-regulated in adult ovaries compared with neonate ovaries.
