Project description:The goal of this study was to investigate the roles of Butyrophilin Subfamily 1 Member A1 (BTN1A1) in terms of the signaling pathway after overexpression of BTN1A1A1 gene. To this end, we conducted NanoString analysis. From NanoString analysis with BTN1A1-overexpressing PC3 cells, we concluded that BTN1A1 play a pivotal role in the regulation of several signaling pathway including Jak-STAT pathway that is involved in processes such as immunity, cell division, cell death and tumor formation.
Project description:Comparison of immune-infiltrated bone marrow samples (n=6) with immune-depleted bone marrow samples (n=17) of pediatric acute myeloid leukemia patients using the Nanostring PanCancer IO 360 panel.
Project description:Histologically normal breast lobules were obtained from non-Hispanic Black women (NHBW) and non-Hispanic White women (NHWW) (n=10 per group) matched by age, BMI, and parity. RNA extracted from FFPE sections was profiled using the NanoString PanCancer IO 360 CodeSet to characterize transcriptional programs associated with group differences in benign breast epithelium.
Project description:RNA from 56 gastric adenocarcinoma was analyzed on the nCounter system using the PanCancer IO 360, a curated panel including 770 genes across key immuno-oncology pathways and processes
Project description:Baseline lobule-enriched FFPE RNA from benign breast biopsies of women aged 45–55 was profiled using NanoString nCounter PanCancer IO 360 and Breast Cancer 360 panels. Sample identifiers were anonymized (ARLI###) for public release; the original internal block codes are retained only in a private key held by the authors. Gene expression was related to the subsequent pace of age-related lobular involution across the menopausal transition.
Project description:The 12 recurrent GBM patients were participated. NanoString nCounter pancancer IO 360 panel (750 genes) assay was conducted with GBM patients tissue which was extracted at postoperative after recurrent event. The goal of this study was to extract significant genes which were associated with overall survival (OS) and durable response within AKC-treated recurrent GBM patients.