Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA sequencing of Tie2 (TEK) silencing in Tie2+ Fibrolast like cells (TF) from the aorta of wild type C57Bl/6J mice.

ABSTRACT: RNA sequencing of Tie2 (TEK) silencing in Tie2+ Fibrolast like cells (TF) from the aorta of wild type C57Bl/6J mice.

PROVIDER: PRJNA777656 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR16766982.fastq.gz	Fastqsanger.gz
	SRR16766983.fastq.gz	Fastqsanger.gz
	SRR16766984.fastq.gz	Fastqsanger.gz
	SRR16766985.fastq.gz	Fastqsanger.gz
	SRR16766986.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 9

Similar Datasets

Tek+ cells from the E10 AGM region of Rictorf/f; Tie2-cre and control

Project description:we performed RNAseq analysis on Rictorf/f; Tie2-cre and control tek+ cells, to determine which hematopoietic genes are activated in the endothelium in the AGM by Rictor.

2017-07-30 | GSE59929 | GEO

RNA sequencing of Tie2 (TEK) silencing in Tie2+ Fibrolast like cells (TF) from the aorta of wild type C57Bl/6J mice.

Project description:Purpose: Our objective is to compare the gene expression pattern in the TF cells transfected with LV-SCR or LV-shTEK-A or LV-shTEK-D invitro.

2023-01-23 | GSE187844 | GEO

Single cell analysis in the adult aorta after Tie2 deletion

Project description:Single cell analysis in the adult aorta after Tie2 deletion

| PRJNA680252 | ENA

Expression data: Venous malformation-causative TIE2-mutations mediate an AKT-dependent decrease in PDGFB

Project description:Comparison of transcriptional profiles of human umbilical vein endothelial cells (HUVECs) expressing wild-type vs. VM-causative mutant forms of TIE2/TEK. The effects of the most common Venous Malformation-causative mutations in the endothelial cell tyrosine kinase receptor: R849W and L914F, were tested. 743 genes were differentially expressed across the four groups. The 80 genes distinguishing between L914F and wild-type TIE2-expressing HUVECs were analyzed in greater detail. 3 batches each of: non-transfected, and wild-type TIE2, R849W-TIE2, and L914F-TIE2 overexpressing HUVECs were compared by exon-array profiling.

2013-06-04 | E-GEOD-46684 | biostudies-arrayexpress

Expression data: Venous malformation-causative TIE2-mutations mediate an AKT-dependent decrease in PDGFB

2013-06-04 | GSE46684 | GEO

Single cell analysis in the adult aorta after Tie2 deletion

Project description:To analyze the Angiopoietin receptor Tie2 on the arterial endothelial cells during atheroclerosis

2023-01-23 | GSE161979 | GEO

Brachypodium distachyon strain:Tek-9 | cultivar:Tek-9

Project description:Brachypodium distachyon strain:Tek-9 | cultivar:Tek-9 Genome sequencing

| PRJNA333777 | ENA

RNA-sequencing of Endothelial Cell Lines Expressing TIE2 WT or Mutant TIE2-L914F

Project description:To investigate the transcriptional effects of venous malformation causative somatic mutation in TIE2 p.L914F mutation on endothelial cells, bulk RNA-sequencing was performed on endothelial cells lines expressing TIE2 wildtype or mutant TIE2-L914F

2025-09-26 | GSE307395 | GEO

Investigation of the possible role of Tie2 pathway and TEK gene in asthma and allergic conjunctivitis

Project description:Tie2, coded by the TEK gene, is a tyrosine kinase receptor and plays a central role in vascular stability. It was suggested that variations in the TEK gene might influence the susceptibility to asthma and allergic conjunctivitis. The aim of this study was to further investigate these suggestions, involving different populations and to study the Tie2 related pathway on a mouse model of asthma. In stage I, 113 SNPs were screened in the TEK gene of the patients in order to search for associations with asthma and allergic conjunctivitis. The top associated SNPs were selected for association studies on the replication cohorts.

2020-02-26 | PRJEB36264 | EVA

Gene expression profiles of TIE2 expressing Monocytes (TEMs)

Project description:To identify the gene expressing profiles of TIE2 expressing Monocytes(TEMs), we have employed the Agilent lncRNA Gene Expression 4Ã180K(Design ID:042818) microarray. Human peripheral blood mononuclear cells (PBMCs) in venous blood from healthy donors were isolated by Lymphoprep (Axis-Shield, Norway). Human monocytes in PBMCs, identified as cells that expressed CD14, were enriched by positive immunomagnetic selection using anti-CD14 MicroBeads (Miltenyi, Germany). TEMs (TIE2+CD14+) and TIE2-Monocytes (Tie2-CD14+) were then isolated by FACS-sorting (Aria II, BD Biosciences) using FITC-conjugated anti-CD14 (BD Biosciences, USA) and APC-conjugated anti-TIE2 (R&D System, USA) antibodies.Three TEMs samples together with their paried TIE2-Monocytes were detected.Expressions of sixteen genes (CDKN1A, FDXR, SESN1, BBC3 and PHPT1) from this signature was quantified in the same RNA samples by real-time PCR, confirming low variability between donors as well as the predicted radiation response pattern. The gene expressions of three independent paried TEMs and TIE2- Monocytes samples from different donors were measured.

2017-05-17 | E-GEOD-57783 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data