Project description:To explore the molecular mechanism of the DNA phosphorothioate modification-dependent restriction system, the transcriptomes of Salmonella enterica serovar Cerro 87 wild-type and its modification or restriction genes deletion mutants were compared by microarray analysis. Global gene expression in three strains, Salmonella enterica serovar Cerro 87 wild-type and its modification or restriction genes deletion mutants, were measured at three different growth state, respectively. Three independent experiments were performed at each condition.
Project description:To explore the molecular mechanism of the DNA phosphorothioate modification-dependent restriction system, the transcriptomes of Salmonella enterica serovar Cerro 87 wild-type and its modification or restriction genes deletion mutants were compared by microarray analysis.
Project description:This study compares the global transcriptomes of highly pathogenic bovine-adapted S. enterica serovar Dublin and the less pathogenic bovine-adapted serovar Cerro during interactions with bovine epithelial cells, to identify genes that impact serovar-related outcomes of S. enterica infections in dairy animals
Project description:Single-molecule read technologies allow for detection of epigenomic base modifications during routine sequencing by analysis of kinetic data during the reaction, including the duration between base incorporations at the elongation site (the "inter-pulse duration.") Methylome data associated with a closed de novo bacterial genome of Salmonella enterica subsp. enterica serovar Javiana str. CFSAN001992 was produced and submitted to the Gene Expression Omnibus.
Project description:FabR ChIP-chip on Salmonella enterica subsp. enterica serovar Typhimurium SL1344 using anti-Myc antibody against strain with chromosomally 9Myc-tagged FabR (IP samples) and wildtype strain (mock IP samples)
Project description:Single-molecule read technologies allow for detection of epigenomic base modifications during routine sequencing by analysis of kinetic data during the reaction, including the duration between base incorporations at the elongation site (the "inter-pulse duration.") Methylome data associated with a closed de novo bacterial genome of Salmonella enterica subsp. enterica serovar Javiana str. CFSAN001992 was produced and submitted to the Gene Expression Omnibus. Single-sample sequencing and base modification detection of cultured isolate of a foodborne pathogen.