Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single cell characterization of the cellular landscape of acral melanoma identifies novel targets for immunotherapy

ABSTRACT: Single cell characterization of the cellular landscape of acral melanoma identifies novel targets for immunotherapy

PROVIDER: PRJNA784961 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR17075100.fastq.gz	Fastqsanger.gz
	SRR17075101.fastq.gz	Fastqsanger.gz
	SRR17075102.fastq.gz	Fastqsanger.gz
	SRR17075103.fastq.gz	Fastqsanger.gz
	SRR17075104.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 68

Similar Datasets

Single cell characterization of the cellular landscape of acral melanoma identifies novel targets for immunotherapy

Project description:Acral melanoma is a rare subtype of melanoma that arises on the non-hair-bearing skin of the palms, soles and nail beds. In this study, we used single cell RNA-seq (scRNA-seq) to map the transcriptional landscape of acral melanoma and identify novel immunotherapeutic targets.

2022-02-14 | GSE189889 | GEO

Acral Melanoma

Project description:Acral Melanoma

| PRJNA682608 | ENA

Acral Melanoma microRNA Ratio Classification

Project description:We performed microRNA sequencing of primary human FFPE Acral Melanoma (AM), Cutaneous Melanoma (CM), Acral Nevi (AN), and Cutaneous Nevi (CN). We found that previously identified ratios of microRNAs, particularly miR-21-5p and miR-211-5p, were able to accurately classify benign and malignant melanocytic neoplasia, both in non-acral cutaneous melanomas and nevi (CM vs CN), as well as matched acral melanoma and nevi (AM vs AN). Receiver operating characteristic area under the curve (AUC) of Ensemble models trained using these microRNA ratios demonstrated AUCs of 0.88-0.90 across these melanoma subtypes, suggesting the potential utility of these ratios as a biomarker of malignancy in melanocytic neoplasia.

2024-08-14 | GSE266413 | GEO

Genome wide analysis of acral melanoma

Project description:This SuperSeries is composed of the following subset Series: GSE28909: Genome wide analysis of acral melanoma (Illumina) GSE28910: Genome wide analysis of acral melanoma (Affymetrix) Refer to individual Series

2011-12-13 | E-GEOD-28913 | biostudies-arrayexpress

Genome wide analysis of acral melanoma (Affymetrix)

Project description:Genotyping of a matched normal, primary and metastatic acral melanoma DNA from blood and one matched Primary and one metastatic acral melanoma was genotyped on Affmetrix SNP6

2011-12-13 | E-GEOD-28910 | biostudies-arrayexpress

Genome wide analysis of acral melanoma (Illumina)

Project description:Assessment of mutation on expression levels Transcriptomic profile of a matched primary and metastatic acral melanoma One Primary and one metastatic acral melanoma transcript expression were assayed (no matched normal)

2011-12-13 | E-GEOD-28909 | biostudies-arrayexpress

Genome wide analysis of acral melanoma (Affymetrix)

Project description:Genotyping of a matched normal, primary and metastatic acral melanoma

2011-12-13 | GSE28910 | GEO

Genome wide analysis of acral melanoma (Illumina)

Project description:Assessment of mutation on expression levels Transcriptomic profile of a matched primary and metastatic acral melanoma

2011-12-13 | GSE28909 | GEO

Molecular characterization of acral melanoma

Project description:Molecular characterization of acral melanoma

| PRJNA471577 | ENA

Acral Melanoma microRNA Ratio Classification

Project description:Acral Melanoma microRNA Ratio Classification