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Identification of differently expressed mRNAs in LNPPS overexpression bladder cancer cells

ABSTRACT: Identification of differently expressed mRNAs in LNPPS overexpression bladder cancer cells

PROVIDER: PRJNA788932 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR17259727_1.fastq.gz	Fastqsanger.gz
	SRR17259727_2.fastq.gz	Fastqsanger.gz
	SRR17259728_1.fastq.gz	Fastqsanger.gz
	SRR17259728_2.fastq.gz	Fastqsanger.gz
	SRR17259729_1.fastq.gz	Fastqsanger.gz

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Identification of differently expressed mRNAs in LNPPS overexpression bladder cancer cells

Project description:In this study, we aimed to explore RNAs profiling regulated by LNPPS in bladder cancer. RNA-seq analysis of three pairs of LNPPS-overexpressing 5637 cells and control cells was completed in this project. A total of 17.6Gb raw data was obtained. In concluion, our data showed that the overexpression of LNPPS caused the significantly upregulation of 82 mRNAs, and the downregulation of 102 mRNAs (|Log2FC|>1.5, p<0.05). Further studies will focus on the potential regulatory mechanisms of these significantly differently expressed mRNAs in the LNPPS-mediated development of bladder cancer.

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