Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

IL-13 signaling via epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis

ABSTRACT: IL-13 signaling via epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis

PROVIDER: PRJNA800267 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR17732870.fastq.gz	Fastqsanger.gz
	SRR17732871.fastq.gz	Fastqsanger.gz
	SRR17732872.fastq.gz	Fastqsanger.gz
	SRR17732873.fastq.gz	Fastqsanger.gz
	SRR17732874.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

IL-13 involvement in eosinophilic esophagitis: transcriptome analysis

Project description:3 eosinophilic esophagitis biopsies, cultured and stimulated with IL-13 : each of them was either left unstimulated or stimulated (100ng for 48h) We used microarray to uncover the IL-13-induced genes in esophageal epithelial cells of the esophagus Keywords: treated vs non treated

2007-12-21 | GSE8853 | GEO

Epithelial overexpression of IL-33 induces eosinophilic esophagitis dependent on IL-13

Project description:To examine the role of the epithelial-derived cytokine, IL-33, in eosinophilic esophagitis (EoE) pathogenesis we developed a novel mouse model (EoE33) in which a secreted and active form of IL-33 is overexpressed by esophageal epithelial cells.

2023-12-18 | GSE238122 | GEO

Transcription profiling of human eosinophilic esophagitis biopsies, cultured and stimulated with IL-13

Project description:3 eosinophilic esophagitis biopsies, cultured and stimulated with IL-13 : each of them was either left unstimulated or stimulated (100ng for 48h); We used microarray to uncover the IL-13-induced genes in esophageal epithelial cells of the esophagus Experiment Overall Design: 3 biopsies from EE patients were obtained and primary epithelial cell were cultured and either left unstimulated or stimulated with IL-13 followed by RNA extraction and hybridization on Affymetrix microarrays.

2008-06-20 | E-GEOD-8853 | biostudies-arrayexpress

IL-13 signaling via epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis II

Project description:IL-13 signaling via epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis II

| PRJNA801660 | ENA

Epithelial overexpression of IL-33 induces eosinophilic esophagitis dependent on IL-13

Project description:Epithelial overexpression of IL-33 induces eosinophilic esophagitis dependent on IL-13

| PRJNA997994 | ENA

Dupilumab normalizes the eosinophilic esophagitis disease transcriptome

Project description:Dupilumab, which blocks interleukin (IL)-4 and IL-13 signaling, is approved in eosinophilic esophagitis (EoE) and several other type 2 inflammatory diseases. We show that dupilumab normalizes the dysregulated esophageal transcriptome in pediatric, adolescent, and adult patients with EoE, including both eosinophil-related and eosinophil-independent biologic pathways.

2025-10-01 | GSE303734 | GEO

TaqMan microRNA array of human serum from children with eosinophilic esophagitis

Project description:Serum from children with active and inactive treated eosinophilic esophagitis was analyzed for detection of microRNA Individual serum samples from children with eosinophilic esophagitis were analyzed for detection of microRNA. (n=5 for active EoE and n=5 for inactive EoE)

2014-09-01 | E-GEOD-55793 | biostudies-arrayexpress

Nanostring nCounter human miRNA assay (v1) of eosinophilic esophagitis

Project description:Nanostring nCounter Human miRNA assay (v1) of esophageal mucosal biopsies from children with eosinophilic esophagitis and controls Individual esophageal mucosal biopsies from children with eosinoniphilic esophagitis and controls were analysed for detection of microRNA

2014-09-01 | E-GEOD-55794 | biostudies-arrayexpress

The IL-33 receptor ST2 is expressed on IL-4+ and IL-13+ human tissue eosinophils in eosinophilic esophagitis

Project description:The IL-33 receptor ST2 is expressed on IL-4+ and IL-13+ human tissue eosinophils in eosinophilic esophagitis

| PRJNA704920 | ENA

Adult Eosinophilic Esophagitis Registry Atlas

Project description:Adult Eosinophilic Esophagitis Registry Atlas

| PRJNA1083652 | ENA