Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-sequencing of HGC27 cells with and without FN1 3' UTR overexpression

ABSTRACT: RNA-sequencing of HGC27 cells with and without FN1 3' UTR overexpression

PROVIDER: PRJNA810189 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR18134951_1.fastq.gz	Fastqsanger.gz
	SRR18134951_2.fastq.gz	Fastqsanger.gz
	SRR18134952_1.fastq.gz	Fastqsanger.gz
	SRR18134952_2.fastq.gz	Fastqsanger.gz
	SRR18134953_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

RNA-sequencing of HGC27 cells with and without FN1 3' UTR overexpression

Project description:As a key protein in the tumor microenvironment, FN1 has been proven to promote cancer in a variety of cancer species. However, in our previous study on gastric cancer, it was found that FN1 protein expression in patient tissues was not significantly correlated with prognosis, and clinical data analysis was only correlated with T stage of gastric cancer. Analysis of the relationship between FN1 mRNA expression level and prognosis by TCGA-STAD database revealed that high FN1 mRNA expression was significantly correlated with poor prognosis. Moreover, many miRNA binding sites were found on FN1 3' UTR by database prediction, so we speculated that FN1 played different functions at mRNA and protein levels, and FN1 3' UTR might function as ceRNA. At present, FN1 3' UTR overexpression has been proved to significantly promote the invasion and metastasis of gastric cancer in vivo and in vitro, and its effect is stronger than FN1 protein. Therefore, in this study, transcriptome sequencing of FN1 3' UTR after overexpression was carried out to further explore its cancer-promoting mechanism.

2022-02-27 | GSE197422 | GEO

miRNA-sequencing of HGC27 and AGS cells with FN1 3' UTR overexpression

Project description:As a key protein in the tumor microenvironment, FN1 has been proven to promote cancer in a variety of cancer species. However, in our previous study on gastric cancer, it was found that FN1 protein expression in patient tissues was not significantly correlated with prognosis, and clinical data analysis was only correlated with T stage of gastric cancer. Analysis of the relationship between FN1 mRNA expression level and prognosis by TCGA-STAD database revealed that high FN1 mRNA expression was significantly correlated with poor prognosis. Moreover, many miRNA binding sites were found on FN1 3' UTR by database prediction, so we speculated that FN1 played different functions at mRNA and protein levels, and FN1 3' UTR might function as ceRNA. At present, FN1 3' UTR overexpression has been proved to significantly promote the invasion and metastasis of gastric cancer in vivo and in vitro, and its effect is stronger than FN1 protein. Therefore, in this study, miRNA sequencing, which was used to find those miRNAs bound to FN1 3’UTR, was carried out to further explore its cancer-promoting mechanism.

2022-02-27 | GSE197423 | GEO

miRNA-sequencing of HGC27 and AGS cells with FN1 3' UTR overexpression

Project description:miRNA-sequencing of HGC27 and AGS cells with FN1 3' UTR overexpression

| PRJNA810188 | ENA

RNA-sequencing of HGC27 cells with and without linc01133 overexpression

Project description:RNA-sequencing of HGC27 cells with and without linc01133 overexpression

| PRJNA790631 | ENA

RNA-seq and miRNA-seq of gastric cancer cell lines after overexpression of FN1 3' UTR

Project description:RNA-seq and miRNA-seq of gastric cancer cell lines after overexpression of FN1 3' UTR

| PRJNA810186 | ENA

Genome-wide maps in MCF-7 cells with six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression or not

Project description:Analysis of MCF-7 cells following six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression. Overexpression of six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR positively regulates the abundance of embryonic stem cell function. Results provide insight into the role of six2 mediated-regulation on the ceRNA network between CYP4Z1 and pseudogene CYP4Z2P in breast cancer stemness.

2019-03-10 | GSE116984 | GEO

Genome-wide loop structure analysis in HGC27 gastric cancer cell.

Project description:We analysed loop structure between gene promoters and enhancers in HGC27 cell using H3K27ac HiChIP.

2025-03-04 | GSE198689 | GEO

Gene expression profile of HGC27 gastric cancer cell p53 KO and KD

Project description:HGC27 gastric cancer cells were manipulated to express mutant p53

2019-06-07 | GSE132333 | GEO

Tumor suppressive long non-coding RNA AFDN-DT inhibits gastric cancer invasion via transcriptional regulation

Project description:We identifed genes differentially expression in HGC27 cells withor without AFDN-DT overexpression

2020-04-17 | GSE139326 | GEO

RNA-seq of Mycobacterium smegmatis MC2-155 with or without inducible overexpression of Mtb RpfB UTR with Atc

Project description:RpfB is one of five resuscitation promoting factors in Mycobacterium tuberculosis. We previously published data indicating the 5' UTR of the gene contains a regulatory riboswitch with an unknown (at the time) ligand. We overexpressed the switch in Mycobacterium smegmatis (which does not contain the rpfB gene), reasoning that overexpression of the switch would s sequester the unknown ligand, giving rise to a phenotype that would help us identify it.

2024-08-02 | E-MTAB-14260 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data