Project description:Myocardial infarction (MI), the most severe manifestation of coronary artery disease, is a multifactorial pathophysiologic process. Here, we constructed a MI mouse model through ligation of the proximal left anterior descending coronary artery. Then we detected and analysed multi-omics (transcriptome and proteome) at different time points (Control, 10 mininte, 1 hour, 6 hour, 24 hour and 72 hour) after MI. Immune-related pathway, pyroptosis pathway, and autophagy pathway r were significantly increased after MI.

2021-09-14 | GSE153494 | GEO

GUARDIAN: Mexican-American Coronary Artery Disease Study (MACAD)

Project description:GUARDIAN: Mexican-American Coronary Artery Disease Study (MACAD)

| PRJNA392714 | ENA

Post Coronary Artery Bypass Graft Study (CABG-BioLINCC)

Project description:Post Coronary Artery Bypass Graft Study (CABG-BioLINCC)

| PRJNA1453573 | ENA

Post Coronary Artery Bypass Graft Study (CABG-BioLINCC)

Project description:Post Coronary Artery Bypass Graft Study (CABG-BioLINCC)

| PRJNA1453574 | ENA

Trans-omics analyses identify the biochemical network of LPCAT1 associated with coronary artery disease

Project description:This study used a trans-omics approach—combining genome-wide SNP analysis and metabolomics—to distinguish coronary artery disease (CAD) patients from high-risk and healthy individuals. It identified declining plasma phospholipids as potential biomarkers, linked key SNPs and genes (notably LPCAT1) to lipid changes, and developed a machine-learning model that accurately predicts CAD (AUC = 0.917). The results highlight the role of phospholipid metabolism and genetic variation in CAD progression.

2025-07-28 | GSE303414 | GEO

LncRNA expression profiling for 6 human monocytes samples from Coronary Artery Disease patients and non Coronary Artery Disease patients

Project description:The human LncRNA microarray analysis of the 6 monocytes samples from Coronary Artery Disease patients and non Coronary Artery Disease 3 Coronary Artery Disease patients and 3 non-Coronary Artery Disease donors

2015-06-05 | E-GEOD-69587 | biostudies-arrayexpress

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