Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptomic effects of corticosterone on male and female skeletal muscle

ABSTRACT: Transcriptomic effects of corticosterone on male and female skeletal muscle

PROVIDER: PRJNA837263 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR19171720.fastq.gz	Fastqsanger.gz
	SRR19171721.fastq.gz	Fastqsanger.gz
	SRR19171722.fastq.gz	Fastqsanger.gz
	SRR19171723.fastq.gz	Fastqsanger.gz
	SRR19171724.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 23

Similar Datasets

Transcriptomic effects of corticosterone on male and female skeletal muscle

Project description:Aim: To investigate the sexual dimorphic effects of corticosterone on skeletal muscle Methods: Male and female mice were exposed to high levels of corticosterone by implantation of 50 mg slow-release pellets. After two weeks, quadriceps muscle was isolated and snap-frozen. Total RNA was isolated and send for 100 bp paired-end sequencing by BGI.

2022-08-03 | GSE202787 | GEO

Skeletal muscle adaptations in response to continuous corticosterone exposure and pharmacological inhibition of lipolysis

Project description:Purpose: to identify adaptations in skeletal muscle gene expression following two weeks of corticosterone treatment with and without ATGL inhibition.

2023-06-08 | GSE226262 | GEO

Effect of Small Mouse Cage Intervention on skeletal muscle gene expression, male and female

Project description:Adult male and female C56BL6J mice were subjected to 8 weeks of small mouse cage (SMC) intervention to model physical inactivity. Widely-used physical inactivity models such as hindlimb unloading and immobilization do not phenocopy metabolic adaptations that occur with human sedentary behavior, whereas many aspects of metabolic adaptations with SMC appear to reproduce this effect. The RNAseq analyses were performed in muscles from these mice to capture changes in skeletal muscle gene expression landscape.

2024-03-06 | GSE260612 | GEO

The effects of testosterone and corticosterone treatment on gene expression in germinal discs of the laying hen

Project description:Previous work has suggested that the hormones testosterone and corticosterone influence the process of meiotic segregation in the ovarian follicles of laying hens, ultimately influencing whether the resulting egg produces a male or female chick. We tested whether treatment with testosterone and/or corticosterone stimulated changes in the expression of genes that may influence the process of meiotic segregation as a next step towards understanding the mechanism by which these hormones may play a role in sex ratio adjustment in birds.

2020-04-13 | GSE131363 | GEO

Effect of Small Mouse Cage Intervention on skeletal muscle gene expression, male and female

Project description:Effect of Small Mouse Cage Intervention on skeletal muscle gene expression, male and female

| PRJNA1082337 | ENA

Estrogen receptor β regulates skeletal muscle mass and muscle stem cell proliferation in young female mice

Project description:The female sex hormone estrogens plays a critical role in maintaining muscle mass and muscle stem cell (MuSCs) functions. However, it is still unclear about downstream pathways of estrogens including its receptors that are expressed in both skeletal muscle tissue and MuSCs. To study the specific role of estrogen receptor β (ERβ), one of two main types of estrogen receptors, in skeletal muscle and MuSCs, we generated muscle-specific ERβ-knockout (mKO) mice and muscle stem cell-specific ERβ-knockout (scKO) mice. Here, we show that muscle-specific ERβ-deficient induced decreased muscle strength and fast-type muscle mass in young female mice. Furthermore, muscle stem cell-specific ERβ-deficient young female mice but not male exhibited impaired muscle regeneration ability after acute muscle injury, accompanied by a decreased proliferation rate of muscle stem cells. RNA sequencing analysis showed that the loss of ERβ in muscle stem cells changes the expression of cell cycle associated genes and niche component factors including laminin and collagen. Thus, our characterization of mKO and scKO mice indicate that the estrogen-ERβ pathway is a sex-specific regulatory mechanism that controls both skeletal muscle mass and the proliferation of muscle stem cell in females and could be of importance in a therapeutic context.

2020-03-31 | GSE135837 | GEO

male and female poplar leaves phosphoproteome

Project description:Nitrogen is a key factor impacting plant physiological processes and protein abundance. Although many proteins were changed substantially in poplar under N deficiency, the post-translational modifications in male and female poplars are still unclear. Therefore, we selected male and female poplars and analysed the changes of protein phosphorylation in response to N-deficient conditions.

2020-01-31 | PXD016397 | Pride

Skeletal muscle from male C57BL/6J mice at 3-month-old or 24-month-old

Project description:Skeletal muscle from male C57BL/6J mice at 3-month-old or 24-month-old

2025-07-26 | PXD066632 |

The osteocyte transcriptome during post-natal skeletal maturation in male and female mice

Project description:The osteocyte transcriptome during post-natal skeletal maturation in male and female mice

| PRJEB30049 | ENA

Plasma proteomic profile by regular training in male and female basketball players: a preliminary study

Project description:Aim of the present study is to identify sex-related sport adaptation proteins in female and male basketball players using proteomics approach on plasma samples withdraw from athletes during in-season training period but far from a competition. A cohort of 20 professional basketball players, 10 females (BF) and 10 males (BM), and 20 sedentary males (10 CM) and females (10 CF) as control, of comparable age and BMI were involved in this study. Protein profiles of plasma samples obtained from BM, BF, CM and CF were analysed by 2-DE. Differentially expressed proteins were identified by mass spectrometry. The computational 2-DE gel image analysis pointed out 33 differentially expressed protein spots (ANOVA p-value<0.05) and differences between male and female are more evident among the players than controls. The expression profile of 54.5% of the total proteins is affected by the sport activity. 14 proteins are differentially expressed in basket female players in comparison with their relative controls while 7 are differentially expressed in basket male players in comparison with their controls. In conclusion, we identify in female athletes a reduction in proteins related to transcription regulation, most of these modulate chronic inflammation confirming the anti-inflammatory effect of regular training in female muscle metabolism. In male and female athletes, we found a decrease in Transthyretin involved in muscle homeostasis and regeneration and Dermcidin a stress-induced myokine linked to inflammatory and it will be interesting to fully understand the role of its different isoforms in male and female skeletal muscle contraction.

2022-05-20 | PXD031050 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data