Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Comparative Transcriptome Analysis Reveals Gene Expression and Regulatory Characteristics of Broad-spectrum Immunity to Leaf Rust in Wheat-Agropyron cristatum 2P Addition Lines

PROVIDER: PRJNA838495 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR19217565_1.fastq.gz	Fastqsanger.gz
	SRR19217565_2.fastq.gz	Fastqsanger.gz
	SRR19217566_1.fastq.gz	Fastqsanger.gz
	SRR19217566_2.fastq.gz	Fastqsanger.gz
	SRR19217567_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Project description:wheat-A. cristatum 2P translocation line

| PRJNA1024063 | ENA

Project description:Agropyron cristatum sequencing

| PRJNA801633 | ENA

Agropyron cristatum

Project description:Agropyron cristatum Organism overview

| PRJNA308028 | ENA

Agropyron cristatum genome

Project description:Agropyron cristatum Z559 genome

| PRJEB91701 | ENA

Agropyron cristatum

Project description:Agropyron cristatum 6P chromosome assembly

| PRJNA1283285 | ENA

Agropyron cristatum

Project description:Agropyron cristatum Raw sequence reads

| PRJNA348756 | ENA

Agropyron cristatum

Project description:Agropyron cristatum Raw sequence reads

| PRJNA382183 | ENA

Agropyron cristatum

Project description:Agropyron cristatum Raw sequence reads

| PRJNA777792 | ENA

Streptococcus pneumoniae endopeptidase O (PepO) induces trained immunity to defend the host against numerous pathogen infections

Project description:Antibiotic resistance and the pandemic of infectious diseases pose major hazards to human health. As a novel anti-infection strategy, trained immunity has a promising future. Recombinant Streptococcus pneumoniae Endopeptidase O (rPepO) is a novel trained immunity inducer that is a highly effective broad-spectrum anti-infective molecule. Here, we demonstrate that rPepO training induces a protective effect by improving the function of several immune cells. rPepO trains macrophages in the periphery to improve their immunological response. In addition, macrophage-derived complement C3 stimulates B lymphocytes to bolster the host's initial line of defense. While trained-macrophage-derived G-CSF changes the host's hematopoiesis and promotes central trained immunity. The "trained" label is found on freshly differentiated mononuclear macrophages, which also possess significantly enhanced anti-infective properties. Consequently, our research reveals that rPepO can induce peripheral and central trained immunity and possesses broad-spectrum and durable antimicrobial characteristics.

2023-12-31 | GSE222201 | GEO

Project description:A five-transgene cassette confers broad-spectrum resistance to a fungal rust pathogen in wheat

| PRJNA624003 | ENA