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Kytococcus schroeteri

ABSTRACT: Kytococcus schroeteri overview

PROVIDER: PRJNA844447 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR9323812_1.fastq.gz	Fastqsanger.gz
	SRR9323812_2.fastq.gz	Fastqsanger.gz

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Kytococcus schroeteri

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Kytococcus schroeteri endocarditis.

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Emergence of the opportunistic bacteria, Kytococcus schroeteri in the brown rat, Rattus norvegicus.

Project description:Emergence of the opportunistic bacteria, Kytococcus schroeteri in the brown rat, Rattus norvegicus.

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Draft Genome Sequence of Kytococcus schroeteri Strain H01, Isolated from Human Skin.

Project description:Kytococcus schroeteri strain H01 was isolated from the skin of a healthy volunteer who underwent erythromycin treatment for a skin disorder 1 year prior. The draft genome consists of 2.38 Mb, a G+C content of 73.06%, and 2,221 protein coding sequences. This is the first genome characterization of a K. schroeteri strain isolated from human skin.

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Insight into <i>Kytococcus schroeteri</i> Infection Management: A Case Report and Review.

Project description:BackgroundKytococcus schroeteri is a member of normal skin microflora, which can cause lethal infections in immunosuppressed hosts. In this review we attempted to draw patterns of its pathogenicity, which seem to vary regarding host immune status and the presence of implantable devices. Evidence suggests this pathogen houses many resistance-forming proteins, which serve to exacerbate the challenge in curing it. Available information on K. schroeteri antibacterial susceptibility is scarce. In this situation, a novel, genome-based antibiotic resistance analysis model, previously suggested by Su et al., could aid clinicians dealing with unknown infections. In this study we merged data from observed antibiotic resistance patterns with resistance data demonstrated by DNA sequences.MethodsWe reviewed all available articles and reports on K. schroeteri, from peer-reviewed online databases (ClinicalKey, PMC, Scopus and WebOfScience). Information on patients was then subdivided into patient profiles and tabulated independently. We later performed K. schroeteri genome sequence analysis for resistance proteins to understand the trends K. schroeteri exhibits.ResultsK. schroeteri is resistant to beta-lactams, macrolides and clindamycin. It is susceptible to aminoglycosides, tetracyclines and rifampicin. We combined data from the literature review and sequence analysis and found evidence for the existence of PBP, PBP-2A and efflux pumps as likely determinants of K. schroeteri.ConclusionsReviewing the data permits the speculation that baseline immune status plays a role in the outcome of a Kytococcal infection. Nonetheless, our case report demonstrates that the outcome of a lower baseline immunity could still be favorable, possibly using rifampicin in first-line treatment of infection caused by K. schroeteri.

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First report of chronic implant-related septic arthritis and osteomyelitis due to Kytococcus schroeteri and a review of human K. schroeteri infections.

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