Project description:Here, we report that chemical-based external stimulation reprograms human BJs to generate human induced FiNs. Using transcriptome,and chromatin accessibility, we identified the cells exhibited key features of FiNs in transcriptomic profiles, epigenetic status. In addition, we also analyzed the reprogramming process.
Project description:Here, we report that chemical-based external stimulation reprograms human BJs to generate human induced FiNs. Using transcriptome,and chromatin accessibility, we identified the cells exhibited key features of FiNs in transcriptomic profiles, epigenetic status. In addition, we also analyzed the reprogramming process.
Project description:Here, we report that chemical-based external stimulation reprograms human BJs to generate human induced FiNs. Using transcriptome,and chromatin accessibility, we identified the cells exhibited key features of FiNs in transcriptomic profiles, epigenetic status. In addition, we also analyzed the reprogramming process.
Project description:Here, we report that chemical-based external stimulation reprograms human somatic cells to generate human induced pluripotent stem cells. Using transcriptome, chromatin accessibility and DNA methylome profiling, we identified the cells exhibited key features of embryonic stem cells in transcriptomic profiles, epigenetic status. In addition, we also analyzed the reprogramming process.
Project description:Here, we report that chemical-based external stimulation reprograms human somatic cells to generate human induced pluripotent stem cells. Using transcriptome, chromatin accessibility and DNA methylome profiling, we identified the cells exhibited key features of embryonic stem cells in transcriptomic profiles, epigenetic status. In addition, we also analyzed the reprogramming process.
Project description:Here, we report that chemical-based external stimulation reprograms human somatic cells to generate human induced pluripotent stem cells. Using transcriptome, chromatin accessibility and DNA methylome profiling, we identified the cells exhibited key features of embryonic stem cells in transcriptomic profiles, epigenetic status. In addition, we also analyzed the reprogramming process.