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Wildtype and methyl-deficient Puf4 RIP-seq in Cryptococcus neoformans

ABSTRACT: Wildtype and methyl-deficient Puf4 RIP-seq in Cryptococcus neoformans

PROVIDER: PRJNA851473 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR19775714_1.fastq.gz	Fastqsanger.gz
	SRR19775714_2.fastq.gz	Fastqsanger.gz
	SRR19775715_1.fastq.gz	Fastqsanger.gz
	SRR19775715_2.fastq.gz	Fastqsanger.gz
	SRR19775716_1.fastq.gz	Fastqsanger.gz

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Wildtype and methyl-deficient Puf4 RIP-seq in Cryptococcus neoformans

Project description:Puf4 is a pumilio/fbf domain containing RNA binding protein. Our previous work revelated that Puf4 modulates ER stress and anrifungal resistance in C. neoformans. Our recent work showed that Puf4 is targeted by arginine methyltransferases. We investigated the RNA binding network of wildtype Puf4 as well as two mutants that have methyl-deficient (arginine to lysine) mutations.

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