Project description:To evaluate potential off-target effects of the RECKLEEN system, we sequenced the genome of the WT Klebsiella pneumoniae MGH 78578 strain and the Δwzi strain that had been generated using the RECKLEEN system.
Project description:Purpose: The purpose of this study was to investigate the effect of quorum sensing-related luxS gene on the transcription level of Klebsiella pneumoniae FK6768. Methods: We constructed the luxS gene knockout strain of FK6768 and its complement strain, and performed transcriptome sequencing.
Project description:The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (5 strains each) using an integrated application of genomic, transcriptomic, metabolomic and proteomic technologies. The pathogens included in this initiative are: Escherichia coli, Klebsiella pneumoniae complex, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae. This submission pertains to strain AJ218.
Project description:The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (5 strains each) using an integrated application of genomic, transcriptomic, metabolomic and proteomic technologies. The pathogens included in this initiative are: Escherichia coli, Klebsiella pneumoniae complex, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae. This submission pertains to strain KPC2.