Project description:tracheal adenoid cystic carcinoma is one kind of non-small-cell lung cancer with limit treatment options. We used single cell RNA sequencing (scRNA-seq) to analyze the molecular characteristic of tracheal adenoid cystic carcinoma, aiming to recognized this disease deeply and provide potential treatment plan in the future.
Project description:We profiled 8 patients with sinonasal-skull base adenoid cystic carcinoma by single-cell RNA sequencing (10x Genomics) to characterize intratumoral heterogeneity and the immune landscape.
Project description:We performed spatial transcriptomics of a tumor section from a patient post-treatment with adenoid cystic carcinoma of the lacrimal gland.
Project description:Chromatin immunoprecipitation was carried out using an anti-MYB antibody in PDX-derived ACCX11 adenoid cystic carcinoma cells. Input samples were extracted prior to the addition of antibody.
Project description:We profiled 6 patients with sinonasal-skull base adenoid cystic carcinoma by spatial transcriptomics (10x Genomics Visium) to characterize intratumoral heterogeneity and the immune landscape.
Project description:To identify the transcriptomic signature of adenoid cystic carcinoma of the lacrimal gland (LGACC), we performed RNA sequencing on LGACC tumor samples and normal lacrimal gland samples.