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Translating ribosome affinity purification analysis of dopaminergic neurons of the mouse ventral midbrain with age and alpha-synuclein overexpression.

ABSTRACT: Translating ribosome affinity purification analysis of dopaminergic neurons of the mouse ventral midbrain with age and alpha-synuclein overexpression.

PROVIDER: PRJNA889520 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR21866600_1.fastq.gz	Fastqsanger.gz
	SRR21866600_2.fastq.gz	Fastqsanger.gz
	SRR21866700_1.fastq.gz	Fastqsanger.gz
	SRR21866700_2.fastq.gz	Fastqsanger.gz
	SRR21866601_1.fastq.gz	Fastqsanger.gz

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Translating ribosome affinity purification analysis of dopaminergic neurons of the mouse ventral midbrain with age and alpha-synuclein overexpression.

Project description:To investigate the cell type-specific expression features of dopaminergic neurons in ventral midbrain, we generated DAT-TRAP mice. We then performed gene expression profiling analysis using data obtained from RNA-seq of samples collected from 3- and 18-month old mice. OVX were also bred to overexpress human alpha-synuclein. Short and long-read sequencing were performed.

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