Project description:Peri-implantitis prevention remains a significant challenge in implant dentistry. This study evaluated the dual functionality of a curcumin-carbon dot (Cur-CD) complex in enhancing the osteogenic differentiation of rat bone marrow mesenchymal stem cells (rBMSCs) and exerting antibacterial effects. Primary rBMSCs were isolated and divided into control and Cur-CD-treated groups. After 21 days of osteogenic induction, total RNA was extracted for transcriptome sequencing analysis to investigate the molecular mechanisms underlying Cur-CD-promoted osteogenesis. The results demonstrated that Cur-CD significantly enhanced mineralized nodule formation and up-regulated expression of key osteogenic markers (Runx2, OPN, Osterix, OCN), providing evidence for its potential as a bioactive agent for preventing peri-implantitis.
2026-08-12 | GSE343587 | GEO
Project description:16srna sequencing of rat faeces with Lactobacillus rhamnosus intragastric administration
| PRJNA1066995 | ENA
Project description:16sRNA in rat feces of different PCOS models
| PRJNA946903 | ENA
Project description:16sRNA sequencing
| PRJNA723153 | ENA
Project description:16sRNA intestinal sequencing
| PRJNA1227729 | ENA
Project description:Faecl 16sRNA sequencing
| PRJNA809132 | ENA
Project description:16sRNA in rat feces of Control, PCOS and JWBZYQ groups