Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of knockdown of Snai1 on gene expression of EndoFP during in a mouse model of pressure overload.

ABSTRACT: Effect of knockdown of Snai1 on gene expression of EndoFP during in a mouse model of pressure overload.

PROVIDER: PRJNA899476 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR22228143_1.fastq.gz	Fastqsanger.gz
	SRR22228143_2.fastq.gz	Fastqsanger.gz
	SRR22228144_1.fastq.gz	Fastqsanger.gz
	SRR22228144_2.fastq.gz	Fastqsanger.gz
	SRR22228145_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Effect of knockdown of Snai1 on gene expression of EndoFP during in a mouse model of pressure overload.

Project description:To investigate Snai1 in the regulation of EndoFP, we established injection of AAV containing the Snai1_KD plasmid in the mice. We then performed gene expression profiling analysis using data obtained from RNA-seq of 6 different sample 2 weeks after TAC.

2022-11-14 | GSE217528 | GEO

Transcription profiling of mouse model of pressure overload

Project description:Pressure overload (PO) leads first to cardiac hypertrophy and later to heart failure. In mice, PO leads to sex differences in cardiac morphology and function. However, early sex differences in gene regulation that precede sex differences in function have not yet been identified. To identify such changes, we developed a model of PO that is characterized by compensated hypertrophy without sex differences after 2 weeks and by heart failure with sex differences after 9 weeks. We used transverse aortic constriction (TAC) or sham-operation in male and female mice and analyzed gene expression by microarray experiments. Experiment Overall Design: The gene expression induced by pressure overload in female and male mice in comparison to sham operated control mice was investigated. For each of these four conditions four biological replicates were performed and the individual samples were hybridized seperately on Affymetrix RAE 430A GeneChip Arrays.

2008-06-15 | E-GEOD-6970 | biostudies-arrayexpress

Myocardial gene expression in response to pressure overload

Project description:Myocardial deletion of klf4 sensitizes mouse to pressure overload. In order to gain a better understanding of molecular mechanisms of such alterations, we profiled gene expression before and after 3-day of pressure overload (induced by transverse aortic constriction -TAC) in the hearts from MHC-cre (Cre) control and MHC-cre-klf4-deficient (KO) mice. 10wk old male mice was subjected to transverse aortic constriction (TAC) to induce pressure overload or sham operation as control group. After 3 days, heart was removed and total RNA was extracted from apex and subjected for array analysis. Four animals in each group.

2015-07-01 | E-GEOD-61177 | biostudies-arrayexpress

Pressure-Overload Induced Cardiac Hypertrophy

Project description:Aortic banding is an excellent model system to evaluate the process of development of left ventricular hypertrophy in response to hemodynamic stress. The Affymetrix GeneChip MgU74Av1 was used to analyze expression profiles of mice at different time points after surgical intervention for pressure-overload induced hypertrophy. More information about this model may be obtained at http://cardiogenomics.med.harvard.edu/groups/proj1/pages/band_home.html Keywords = Pressure overload, cardiac hypertrophy Keywords: time-course

2002-07-30 | GSE76 | GEO

Pressure overload cardiac hypertrophy

Project description:Expression profiling of hearts from FVB males subjected to cardiac pressure overload by transverse aortic constriction (TAC). TAC performed on 8-10 weeks month old males and females. Hearts examined 30 weeks after surgery. Keywords: ordered

2005-06-29 | GSE2459 | GEO

Myocardial gene expression in response to pressure overload

2015-07-01 | GSE61177 | GEO

Differential gene expressions in the hypertensive heart using pressure-overload model

Project description:Differential gene expressions were constructed through expression profiling of a total of 26,423 genes in the hypertrophic heart followed by pressure-overload model, then 537 significant differential genes were filtered based on the criteria (p<0.05 and fold change >1.5).

2016-11-04 | GSE89493 | GEO

Effect of pressure-overload on cardiac endothelial cells in Balb/c mice

Project description:We performed single-cell RNA-seq analysis of FACS-sorted cardiac blood vascular and lymphatic endothelial cells in the heart of Balb/c female mice in a model of pressure-overload.

2025-09-30 | GSE291154 | GEO

Effect of pressure-overload on cardiac endothelial cells in C57BL6/J mice

Project description:We performed single-cell RNA-seq analysis of FACS sorted cardiac blood vascular and lymphatic endothelial cells in the heart of adult C57 female mice in a model of pressure-overload.

2025-10-13 | GSE290576 | GEO

Transcription profiling of mouse pressure overload induced cardiomyopathy time series

Project description:Expression profiles at various time points after surgical intervention for pressure-overload induced cardiac hypertrophy and failure.

2004-06-30 | E-MEXP-105 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data