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UV cross-linking RIP-seq of VSV-GFP-infected HEK293T cells overexpressed PTENα

ABSTRACT: UV cross-linking RIP-seq of VSV-GFP-infected HEK293T cells overexpressed PTENα

PROVIDER: PRJNA903837 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR22356531_1.fastq.gz	Fastqsanger.gz
	SRR22356531_2.fastq.gz	Fastqsanger.gz
	SRR22356532_1.fastq.gz	Fastqsanger.gz
	SRR22356532_2.fastq.gz	Fastqsanger.gz

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UV cross-linking RIP-seq of VSV-GFP-infected HEK293T cells overexpressed PTENα

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CLIP-seq of VSV-infected HEK293T cells overexpressed PTENα

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HyperTRIBE assay of VSV-GFP-infected HEK293T cells overexpressing ADAR1-CD, PTENα-N(WT)-ADAR1-CD, or PTENα-N(6R/D)-ADAR1-CD fusion protein

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Project description:In contrast to the ubiquitous expression profile of PTEN, PTENα is predominantly expressed in brain. To study the biological function of PTENα in brain, we employed LCMV to induce murine viral encephalitis model. Through single cell RNA sequencing, we revealed the immunological function of PTENα during viral infection in the brain.

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