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DNA methylation changes from primary cultures through senescence-bypass in Syrian hamster fetal cells initially exposed to benzo[a]pyrene

ABSTRACT: DNA methylation changes from primary cultures through senescence-bypass in Syrian hamster fetal cells initially exposed to benzo[a]pyrene

PROVIDER: PRJNA909278 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR11026960.fastq.gz	Fastqsanger.gz
	SRR11026961.fastq.gz	Fastqsanger.gz
	SRR11026962.fastq.gz	Fastqsanger.gz
	SRR11026963.fastq.gz	Fastqsanger.gz
	SRR11026964.fastq.gz	Fastqsanger.gz

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Chronology of DNA methylation changes through transformation stage leading to senescence by-pass in Syrian hamster fetal primary cells exposed to benzo[a]pyrene

Project description:Purpose: To use reduced representaion bisulfite sequencing to measure differential genome methylation among: 1. cells treated with benzo[a]pyrene (B[a]P) versus vehicle alone (DMSO) using the Syrian Hamster Cell Transformation Assay method; 2. cells originating from normal (Nc) versus morphologically transformed (MTc) colonies; 3. cells in senescence (SEN) versus those that have bypassed senescence (SENbp).

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DNA methylation changes from primary cultures through senescence-bypass in Syrian hamster fetal cells initially exposed to benzo[a]pyrene

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