Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Role of MYC acetylated lysine residues in cell transformation and gene-selective regulation

ABSTRACT: Role of MYC acetylated lysine residues in cell transformation and gene-selective regulation

PROVIDER: PRJNA911991 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR22728200.fastq.gz	Fastqsanger.gz
	SRR22728201.fastq.gz	Fastqsanger.gz
	SRR22728202.fastq.gz	Fastqsanger.gz
	SRR22728203.fastq.gz	Fastqsanger.gz
	SRR22728204.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 75

Similar Datasets

Role of MYC acetylated lysine residues in cell transformation and gene-selective regulation [Rat1A]

Project description:The functions of MYC acetylation have remained unclear. In this study we identified the major lysine residues of MYC that are acetylated by p300 and GCN5 in cancer cell lines and established the requirment of three specific acetyl-lysine (AcK) residues for MYC transformation of Rat1a fibroblasts and MCF10 mammary epithelial cells. We further uncovered gene-selective regulatory functions and conserved genetic programs and biolofical processes regulated by MYC AcK residues in both cell types.

2024-03-20 | GSE220919 | GEO

Role of MYC acetylated lysine residues in cell transformation and gene-selective regulation [MCF10A]

2024-03-20 | GSE220918 | GEO

Role of MYC acetylated lysine residues in cell transformation and gene-selective regulation [MCF10A]

Project description:Role of MYC acetylated lysine residues in cell transformation and gene-selective regulation [MCF10A]

| PRJNA912073 | ENA

Role of MYC acetylated lysine residues in cell transformation and gene-selective regulation [Rat1A]

Project description:Role of MYC acetylated lysine residues in cell transformation and gene-selective regulation [Rat1A]

| PRJNA912074 | ENA

The acetylated lysine residues of Pta

Project description:detection the acetylated lysine residues of Pta (C. ljungdahlii))

2021-09-08 | PXD028235 |

The acetylated lysine residues of AdhE

Project description:detection the acetylated lysine residues of AdhE (C. ljungdahlii))

2021-09-08 | PXD028234 |

The acetylated lysine residues in C. ljungdahlii

Project description:detection the acetylated lysine residues in C. ljungdahlii

2021-09-08 | PXD028233 |

The acetylated lysine residues of Acs (TPA&control)

Project description:Detection the acetylated lysine residues of Acs (between the TPA editor-mediated acetylation (At2-dCas12a-crRNA) and the true acetylation in vivo (dCas12a-crRNA))

2022-02-14 | PXD031674 |

PPARg acetylation governs mammary adenocarcinoma tumor growth via acetylated residues that determine DNA sequence-specific binding

Project description:Peroxisome proliferator-activated receptorg (PPARg), which is expressed in a variety of malignancies, governs biological functions through transcriptional programs. Defining the molecular mechanisms governing selection of canonical versus non-canonical PPARg binding sequences may provide the opportunity to design regulators with distinct functions and side effects. PPARg is acetylated at multiple residues including K268/293 in mouse Pparg2 and the conserved lysine residues (K154/155) in mouse Pparg1. Herein, the PPARg acetylated residues K154/155 were shown to be essential for growth control, and the induction of transcriptional modules governing growth factor signaling, cellular apoptosis and autophagy. The K154/155 residues determined the selection of genome wide DNA binding sites, altering the selection from canonical to non-canonical (C/EBP) DNA sequence specific binding. The gene signature reflecting the acetylation-dependent genomic occupancy provided predictive value in patient survival outcome. Pparg1 participates in ErbB2-induced tumor growth and inflammation and represents a relevant target for therapeutic coextinction.

2025-09-17 | GSE263175 | GEO

The acetylated lysine residues of RNase II (TPA&control)

Project description:detection the acetylated lysine residues of RNase II (between the TPA editor-mediated acetylation (At2-dCas12a-crRNA) and the true acetylation in vivo (dCas12a-crRNA))

2022-02-14 | PXD031675 |

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data