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Transcriptomics study on HepG2 cells treated with 0.001 μM 2,4-D for 0, 10, 30, 360 min

ABSTRACT: Transcriptomics study on HepG2 cells treated with 0.001 μM 2,4-D for 0, 10, 30, 360 min

PROVIDER: PRJNA914258 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR22827923.fastq.gz	Fastqsanger.gz
	SRR22827924.fastq.gz	Fastqsanger.gz
	SRR22827925.fastq.gz	Fastqsanger.gz
	SRR22827926.fastq.gz	Fastqsanger.gz
	SRR22827927.fastq.gz	Fastqsanger.gz

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Transcriptomics study on HepG2 cells treated with 0.001 μM 2,4-D for 0, 10, 30, 360 min

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In vitro transcription studies used in a proof of concept whole transcriptome model predition study - HepG2 cells (4 of 4)

Project description:HpeG2 cells were exposed in triplicate to three agrichemicals for 24hrs at 8 concentrations and a DMSO vehicle control (0.001, 0.003, 0.01, 0.03, 0.1, 0.3, 1, 3, and 10 μM plus DMSO vehicle controls). While a common set of DMSO controls was used, these CEL files were RMA normalized independently with each of the chemical treated groups. Gene expression was measured on an Affymetrix GeneTitan system. The compounds used were fenbuconazole (a.k.a FENB, CAS # 114369-43-6) a triazole fungicide, imazalil (a.k.a. IMAZ, CAS # 35554-44-0), an azole pesticide, and 2,4-dichlorophenoxyacetic acid (a.k.a. 2,4-D or 2-4-D in file names, CAS # 94-75-7), a chlorophenoxy herbicide.

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