Project description:Fetal spina bifida can associate with reduced fetal growth. However, little is known about placental development and function in pregnancies with fetal spina bifida, despite that the placenta is a critical regulator of fetal growth. We used data from a case-control study to determine how the placental transcriptome differs in fetuses with isolated spina bifida (cases), compared to fetuses without any congenital anomalies (controls).
Project description:To evaluate the antihypertensive effect of Ziziphus jujuba (Zi), we conducted a nutrigenomic analysis to examine the changes induced by the administration of the aqueous extracts of these plants on gene expression in mice. Cardiovascular effects were discussed together with antitumoral, anti-inflammatory, antimicrobial and eating behavior effects.
