Project description:To gain a global understanding of the impact of TREM1 silencing, we analyzed the CD45+ tumor infiltrating cells (TICs) of B16F10 tumor-bearing Trem1+/+ and Trem1-/- mice. Utilizing the 10x Genomics Chromium Platform, we analyzed approximately 5390 cells per sample with a coverage rate of 15493 genes per cell.
Project description:Fibrocytes are bone marrow-derived cells expressing fibroblast markers. We used single cell RNA sequencing (scRNA-seq) to analyze the tumor-infiltrating fibrocytes in the lung adenocarcinoma patients
Project description:To investigate how DOPAC suppresses tumors in vivo, we performed single-cell RNA sequencing (scRNA-seq) on CD45+ cells isolated from the tumor tissues of B16-F10-bearing mice.
Project description:Here, we used single cell RNA-sequencing (scRNA-seq) to profile the difference of the CD45 positive cells subgroups infiltrating in MC38-Bap1-Wildtype and MC38-Bap1-Knockout tumor microenvironment on the 10th day of tumor growth in C57BL/6 mice. Additionally, we used scRNA-seq to profile differential gene expression of CD8 T cells and the difference of related signal.
Project description:Gene expression profile at single cell level of B16 and MC38 tumor infiltrating CD45+ TILs isolated from Gpr65-deficient and WT mice
Project description:Gene expression profile at single cell level of sorted CD45+ cells from the GL261 tumor bearing hemisphere, treated with PBS / CSI / CSI+aPD1