Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Differential gene expression in spt-2 mutant worms.

ABSTRACT: Differential gene expression in spt-2 mutant worms.

PROVIDER: PRJNA934522 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR23371626_1.fastq.gz	Fastqsanger.gz
	SRR23371626_2.fastq.gz	Fastqsanger.gz
	SRR23371627_1.fastq.gz	Fastqsanger.gz
	SRR23371627_2.fastq.gz	Fastqsanger.gz
	SRR23371628_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Differential gene expression in spt-2 mutant worms.

Project description:The SPT-2 histone chaperone is involved in the maintenance of chromatin structure during transcription. Here, we performed mRNA-seq to compare gene expression profiles of spt-2 mutant worms. We compare two full spt-2 gene knock-out worm strains (KO-A and KO-B), or a strain expressing an spt-2 allele with reduced binding to histones (M627A), to wild type N2 worms.

2023-02-09 | GSE224801 | GEO

Investigating how the SPT-2 histone chaperone affects chromatin structure in C. elegans.

Project description:Histone chaperones play essential roles in the regulation of chromatin structure. Here, we investigated how the SPT-2 histone chaperone controls chromatin structure and accessibility in C. elegans. To achieve this, we performed ATAC-seq comparing WT N2 worms to spt-2 KO or spt-2 histone binding mutant (spt-2 M627A) worms.

2023-02-09 | GSE224799 | GEO

Identification of GFP-SPT-2 binding sites in the Caenorhabditis elegans genome

Project description:We aimed at investigating whether the newly identified C. elegans SPT2 histone chaperone controls chromatin structure. We decided to profile SPT-2 binding sites to identify its genomic targets and we performed GFP ChIP-seq on a C. elegans strain expressing endogenously GFP-tagged SPT-2, using WT N2 untagged worms as control for binding specificity.

2023-02-09 | GSE224800 | GEO

Expression data comparing wild-type and spt mutant zebrafish tissues at two developmental time points.

Project description:Mesoderm differentiation in zebrafish relies on a complex interaction between transcription factors and signaling pathways. Tbx16 is a t-box transcription factor involved in this interaction. Here, we examine downstream targets of tbx16 in the intermediate mesoderm at the 4/5-somite stage and tail mesoderm at the 21-somite stage by comparing wild-type tissues with tissues from the tbx16 mutant, spadetail (spt).

2010-08-18 | GSE19955 | GEO

Genome-wide DNA accessibility maps and differential gene expression using ChIP-seq, ATAC-seq and RNA-seq for the human secondary fibroblast cell line hiF-T and whole worms with and without knockdown of FACT complex

Project description:To assess the mechanisms by which FACT depletion leads to increased sensitivity of cells to be reprogrammed, we measured the chromatin accessibility landscape using ATAC-seq following mock treatment, SSRP1 knockdown, or SUPT16H knockdown in human fibroblasts and mock, hmg-3 or hmg-4 knockdown in whole worms, and differential gene expression in hmg-3 knockout mutants or following mock, hmg-4, or spt-16 knockdown by RNAseq.

2018-08-29 | GSE98758 | GEO

Comparison of gene expression between wild type (N2) and hlh-30(tm1978) mutant worms

Project description:The hlh-30 gene encodes a C. elegans basic-helix-loop-helix (bHLH) transcription factor; We compared RNA from wild type worms and worms mutant for the hlh-30 gene to identify putative target genes of the HLH-30 transcription factor.

2009-07-24 | GSE15762 | GEO

spt-2 in C. elegans.

Project description:spt-2 in C. elegans.

| PRJNA932727 | ENA

Differential gene expression and splicing in apc mutant zebrafish

Project description:Differential gene expression and splicing in apc mutant zebrafish

| PRJNA983838 | ENA

Expression data of wild-type and mutant worms treated with Cry5Ba

Project description:Expression data of wild-type and mutant worms treated with Cry5Ba

| PRJNA684604 | ENA

Worms

Project description:Worms Raw sequence reads