Project description:RNA-Seq has been an effective method for exploring pathology-associated transcriptional changes in peripheral blood. The main goal of this study is to explore the expression changes of transcripts in the peripheral blood of sick pigs which may be infected with multiple pathogens on farms. We aim to find a subset of marker genes which may be useful candidate genes in the evaluation and prediction of health status in pigs under commercial production conditions.
Project description:The aim of this study was to investigate the response in gene expression before and after exposure to the Benzimidazoles drug flubendazole in adult female Ascaridia galli worms. The nematode Ascaridia galli (order Ascaridida) is an economically important intestinal parasite responsible for increased food consumption, reduced performance, and mortality in commercial poultry production. Parasite control relies on repeated use of dewormers (anthelmintics). Benzimidazoles are currently the only anthelmintic registered against A. galli in the EU and there is an obvious risk that overuse of one drug class may lead to resistance. The worms were collected from a commercial laying hen farms before and on day three during a treatment period of 7 days with flubendazole.
Project description:The study focused on the differential transcriptome of immune organs (i.e., head kidney and spleen) from farmed Atlantic salmon (Salmo salar) fed fermented sunflower meal (FSFM) at 5% and 10% in two commercial farms (CS: coast and FD: fjord location). Data showed that both head kidney and spleen (from fish fed FSFM5% at CS) up-regulated mRNA biogenesis (linked to lipid metabolism and mRNA surveillance) as well as glycosyltransferases (associated with vitamin B6 and lipoic acid metabolism, or pantothenate and CoA biosynthesis). Regarding FD, head kidney from FSFM10% group had up-regulated enzymes (related to lysosome, glutathione metabolism, ribosomes and fatty acid elongation) and the downregulation of transcription machinery and DNA repair/recombination proteins (involved in nucleocytoplasmic transport or spliceosome)
2026-04-16 | GSE307205 | GEO
Project description:Metagenomic survey of commercial and wild bee gut microbiotas
Project description:Comparison of gene expression in dendritic cells (DCs) isolated from tumors of C57BL/6 obtained from Taconic farms vs DCs isolated from tumor of C57BL/6 mice obtained from Jackson Labortaory vs DCs isolated from tumors of C57BL/6 obtained from Taconic farms and orally gavaged with Bifidobacterium prior to tumor implantation
2015-11-12 | GSE73475 | GEO
Project description:16S metagenomics analysis of fecal matter of commercial poultry farms of Faisalabad, Pakistan