Project description:Imprinted macro ncRNAs such as Airn play an important role in silencing protein-coding genes in cis, macro ncRNAs could be a common feature in all imprinted gene clusters. By applying the RNA Expression on Tiling Array (RETA) technique, macro ncRNAs were found to be abundant in 26 known mouse genomic regions containing imprinted genes were detected. All well-known imprinted macro ncRNAs were up-regulated upon depletion of DNA methylation.
Project description:We report chromatin accessibility (ATAC-seq) maps from macro-dissected human kidney cortex and medulla from 3 individuals. The samples were from patients undergoing kidney removal for tumors, but the tissues used in the study itself were normal tissue/cultured cells not involved by tumor.
Project description:We report gene expression (RNA-seq) from macro-dissected human kidney cortex and medulla from 3 individuals. The samples were from patients undergoing kidney removal for tumors, but the tissues used in the study itself were normal tissue/cultured cells not involved by tumor.
Project description:we reported the development of an accurate, easy-to-use and scalable system (SNuBar) for multiplexing single cell ATAC or multi-omics (ATAC&RNA) assays, and applied this method to multiplex therapy combinations in a lung cancer mouse model and macro-spatial regions of normal breast tissues and samples.
2021-10-20 | GSE162798 | GEO
Project description:Macrogenomic analysis of 18 samples