Project description:It has been demonstrated that SC1 (Pluripotin) promotes self-renewal of mouse embryonic stem cells. To better understand miRNAs regulated by SC1 directly or indirectly in mouse embryonic stem cells, we performed next generation sequencing (NGS) to identify small RNAs with expression changes after SC1 treatment.
Project description:It has been demonstrated that SC1 (Pluripotin) promotes self-renewal of mouse embryonic stem cells, however, the target genes of SC1 are not fully understood. To better understand the downstream target genes of SC1, we performed Microarray analysis to identify their downstream targets. The data show the genes regulated by SC1.
Project description:Purpose: determine RNA expression differences in an unbiased fashion between UPS tumors derived from LSL-KrasG12D;Trp53-/- (KP) mice, and UPS tumors derived from LSL-KrasG12D;Trp53-/-;Epas1-/- (KPH2) mice. Epas1 encodes HIF-2alpha protein.
