Project description:Using in vitro directed evolution, we show that mismatch repair-deficient Pseudomonas aeruginosa can engage novel resistance mechanisms to ceftazidime-avibactam.
2021-08-30 | GSE180086 | GEO
Project description:Ceftazidime-Avibactam Resistance Development following Ceftazidime-Avibactam-based therapy in critically-ill patients with infections caused by KPC-producing Klebsiella pneumoniae
| PRJNA839621 | ENA
Project description:Emergence of ceftazidime-avibactam resistance in Klebsiella pneumoniae
Project description:The emergence and spread of polymyxin resistance, especially among Klebsiella pneumoniae isolates threaten the effective management of infections. This study profiled for polymyxin resistance mechanisms and investigated the activity of polymyxins plus vancomycin against carbapenem- and polymyxin-resistant K. pneumoniae.