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ProteomicsIGDQ motogenic peptide gradient induces directional cell migration through integrin (αv)β3 activation in metastatic breast cancer
In the context of breast cancer metastasis study, we have shown in an in vitro model of cell migration that IGDQ-exposing (IsoLeu-Gly-Asp-Glutamine type I Fibronectin motif) monolayers (SAMs) on gold sustain the adhesion of MDA-MB-231 cells by triggering Focal Adhesion Kinase by activating integrins...
ORGANISM(S): Homo sapiens (Human) 
2022-11-08 | PXD024540 | Pride
Breast cancer  tnbc  cell migration  motogenic igdq motif  fibronectin type i  integrin alpha 5  integrin beta 3 
TranscriptomicsRNA-seq on IGDQ-exposed MDA-MB-231 human breast cancer cell line
Breast cancer is the first type of cancer in term of incidence in the world with only 36% of survival at 5 years. This poor prognosis is mainly due to metastasis formation. Cell migration is a key process in nature and the understanding of its complex mechanisms has a crucial importance in biomateri...
ORGANISM(S): Homo sapiens 
2023-03-01 | E-MTAB-10477 | biostudies-arrayexpress
UnknownIGDQ motogenic peptide gradient induces directional cell migration through integrin (αv)β3 activation in MDA-MB-231 metastatic breast cancer cells.
Not available
S-EPMC9241093 | biostudies-literature
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