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ProteomicsComparative Two-Dimensional Polyacrylamide Gel Electrophoresis (2D-PAGE) of Human Milk to Identify Dysregulated Proteins in Breast Cancer
Breast Cancer (BC) remains a major cause of mortality, and early detection is considered important for reducing BC-associated deaths. Early detection of BC is challenging in young women, due to the limitations of mammography on the dense breast tissue of young women. We recently reported results of ...
ORGANISM(S): Homo sapiens (Human) 
2018-06-25 | PXD009860 | Pride
Mass spectrometry Breast cancer Breast milk 2d-page Proteomics Biomarkers 
ProteomicsProteomics analysis of human breast milk by two-dimensional polyacrylamide gel electrophoressi (2D-PAGE) coupled with mass spectrometry to assess breast cancer risk
Breast Cancer (BC) is one of the most common cancers and one of the most common causes for cancer- related mortality. Discovery of protein biomarkers associated with cancer, is considered as important for early diagnosis and prediction of the cancer risk. Protein biomarkers could be investigated by ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-20 | PXD040188 | Pride
Breast cancer  breast milk  biomarkers  protein dysregulation  2d-page  proteomics  mass spec-trometry 
ProteomicsAnalysis of the honeybee sperm proteome using MudPit and 2D PAGE
Honeybee semen was collected by gently squeezing the male abdomens. Samples were pooled and then centrifuged. Pelleted sperm was collected and analysed with both 2D PAGE and gel-free methods. For the 2D PAGE, protein spots were digested using trypsin. Extracted peptides, resolved on a C18 column, we...
ORGANISM(S): Apis mellifera (Honeybee) 
2020-01-17 | PXD000169 | Pride
Sperm. lc-ms 2d page Mudpit Honey bee 
UnknownMatGel: A MATLAB program for quantitative analysis of 2D polyacrylamide electrophoresis (2D-PAGE) protein gel images.
Not available
S-EPMC9703371 | biostudies-literature
TranscriptomicsRole of thioredoxin reductase in the Yap1p-dependent response to oxidative stress
The Saccharomyces cerevisiae Yap1p transcription factor is required for the H2O2-dependent activation of many antioxidant genes including the TRX2 gene encoding thioredoxin 2. To identify factors that regulate Yap1p activity, we carried out a genetic screen for mutants that show elevated expression ...
ORGANISM(S): Saccharomyces cerevisiae 
2005-07-22 | E-GEOD-2977 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mutations in the yeast TRR1 gene encoding thioredoxin reductase
The Saccharomyces cerevisiae Yap1p transcription factor is required for the H2O2-dependent activation of many antioxidant genes including the TRX2 gene encoding thioredoxin 2. To identify factors that regulate Yap1p activity, we carried out a genetic screen for mutants that show elevated expression ...
ORGANISM(S): Saccharomyces cerevisiae 
2005-06-30 | E-SMDB-2716 | biostudies-arrayexpress
UnknownIdentifying the subproteome of kinetically stable proteins via diagonal 2D SDS/PAGE.
Not available
S-EPMC2077256 | biostudies-literature
UnknownMalignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE.
Not available
S-EPMC2955615 | biostudies-literature
Proteomics2D-PAGE coupled with nLC-MS/MS-based identification of differentialy expressed proteins and tumorigenic pathways in MCF7 breast cancer cell line transfected for JTB protein silencing
Identification of new cancer-associated genes/proteins, characterization of their expression vari-ation, the interactomics-based assessment of differentially expressed genes/proteins (DEGs/DEPs), and understanding the tumorigenic pathways and biological processes involved in BC genesis and progressi...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD046265 | Pride
Breast cancer (bc)  mcf7  jtb protein silencing  overexpressed jtb-interactome  downregulated jtb-interactome  tumorigenic pathways 
TranscriptomicsTranscription profiling of chicken histone H1 variant deletion DT40 mutant cell
There are six histone H1 variant in chicken. 01H1/02H1/03H1/.10H1/H1L and H1R. In those variant we forcused on H1L and H1R those molecule were most similar H1 among six H1 variants. we established linker histone H1L and H1R deleted mutant in chicken B-cell derived DT40 cell and assay gene expression...
ORGANISM(S): Gallus gallus 
2008-11-08 | E-GEOD-5114 | biostudies-arrayexpress
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