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ProteomicsCharacterization of novel a-Mangostin and Paeonol derivatives with cancer-selective cytotoxicity
a-Mangostin and Paeonol have shown anti-cancer and anti-inflammatory properties, however these two natural compounds have no clinical value because of their low solubility and low membrane permeability. In this study, we screened chemically synthesized derivatives from these two natural compounds as...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD024999 | Pride
Colorectal cancer  anti-cancer drugs  cancer-selective compounds  natural compound derivatives  colon cancer organoids  paeonol  a-mangostin 
UnknownTargeting transcription factor TCF4 by γ-Mangostin, a natural xanthone.
Not available
S-EPMC6771460 | biostudies-literature
UnknownAlpha-Mangostin: A Potent Inhibitor of TRPV3 and Pro-Inflammatory Cytokine Secretion in Keratinocytes.
Not available
S-EPMC10455244 | biostudies-literature
UnknownTranscriptome Analysis Illuminates a Hub Role of SREBP2 in Cholesterol Metabolism by α-Mangostin.
Not available
S-EPMC7726933 | biostudies-literature
UnknownIn vitro and in vivo studies reveal α-Mangostin, a xanthonoid from Garcinia mangostana, as a promising natural antiviral compound against chikungunya virus.
Not available
S-EPMC7916311 | biostudies-literature
UnknownA novel α-mangostin derivative synergistic to antibiotics against MRSA with unique mechanisms.
Not available
S-EPMC11619392 | biostudies-literature
UnknownUnderstanding of tolerance in TRAIL-induced apoptosis and cancelation of its machinery by α-mangostin, a xanthone derivative.
Not available
S-EPMC4694869 | biostudies-literature
UnknownDelivery of Alpha-Mangostin Using Cyclodextrins through a Biological Membrane: Molecular Dynamics Simulation.
Not available
S-EPMC7321106 | biostudies-literature
UnknownAnti-Acanthamoeba activity of a semi-synthetic mangostin derivative and its ability in removal of Acanthamoeba triangularis WU19001 on contact lens.
Not available
S-EPMC9745913 | biostudies-literature
UnknownThe Nephroprotective Effects of Alpha-Mangostin for Acute Kidney Injury: A Systematic Review and Meta-Analysis.
Not available
S-EPMC12649582 | biostudies-literature
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