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ProteomicsPlasma proteomics defines two reproducible subphenotypes of sepsis-associated acute kidney injury with distinct outcomes
This dataset contains de-identified Olink proteomics data from the ADRENOSS cohort used in the manuscript "Plasma proteomics defines two reproducible subphenotypes of sepsis-associated acute kidney injury with distinct outcomes". The dataset includes plasma protein measurements generated using the O...
ORGANISM(S): Homo sapiens (Human) 
2026-07-28 | PAD000052 | Pride
Olink  affinity proteomics  adrenoss  sepsis-associated acute kidney injury  plasma proteomics  clustering  subphenotypes  biomarkers 
UnknownCirculating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study.
Not available
S-EPMC6305573 | biostudies-literature
UnknownMonitoring circulating dipeptidyl peptidase 3 (DPP3) predicts improvement of organ failure and survival in sepsis: a prospective observational multinational study.
Not available
S-EPMC7885215 | biostudies-literature
UnknownSafety and tolerability of non-neutralizing adrenomedullin antibody adrecizumab (HAM8101) in septic shock patients: the AdrenOSS-2 phase 2a biomarker-guided trial.
Not available
S-EPMC8487806 | biostudies-literature
UnknownKinetics of adrenomedullin pathway activation in a porcine sepsis model and a human cohort of sepsis and septic shock.
Not available
S-EPMC12460767 | biostudies-literature
UnknownA double-blind, placebo-controlled, randomised, multicentre, proof-of-concept and dose-finding phase II clinical trial to investigate the safety, tolerability and efficacy of adrecizumab in patients with septic shock and elevated adrenomedullin concentration (AdrenOSS-2).
Not available
S-EPMC6377571 | biostudies-literature
UnknownProenkephalin A 119-159 (Penkid) Is an Early Biomarker of Septic Acute Kidney Injury: The Kidney in Sepsis and Septic Shock (Kid-SSS) Study.
Not available
S-EPMC6224621 | biostudies-literature
UnknownAdrecizumab, a non-neutralizing anti-adrenomedullin antibody, improves haemodynamics and attenuates myocardial oxidative stress in septic rats.
Not available
S-EPMC6520420 | biostudies-literature
UnknownEffects of enrichment strategies on outcome of adrecizumab treatment in septic shock: Post-hoc analyses of the phase II adrenomedullin and outcome in septic shock 2 trial.
Not available
S-EPMC9751049 | biostudies-literature
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