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ModelsAuer2010 - Correlation between lag time and aggregation rate in protein aggregation
Auer2010 - Correlation between lag time and aggregation rate in protein aggregation This model is described in the article: Insight into the correlation between lag time and aggregation rate in the kinetics of protein aggregation. Auer S, Kashchiev D. Proteins 2010 Aug; 78(1...
2024-09-02 | BIOMD0000000555 | BioModels
TranscriptomicsSingle-gastruloid trancriptomics: control vs glycolysis inhibited at 48h and 96h post-aggregation
Bulk RNA seq of single gastruloids at 48h post-aggregation and 96h post-aggregation. Two different conditions were compared: control vs glycolysis inhibited (6mM 2-deoxy-D-glucosebetween, 24h-48h post aggregation). Aim of the study was to determine short-term effects of glycolysis inhibition on tran...
ORGANISM(S): Mus musculus 
2025-04-10 | E-MTAB-13543 | biostudies-arrayexpress
ModelsProctor2010 - UCHL1 Protein Aggregation
This a model from the article: Modelling the Role of UCH-L1 on Protein Aggregation in Age-Related Neurodegeneration. Proctor CJ, Tangeman PJ, Ardley HC. PLoS One. 2010 Oct 6;5(10):e13175 20949132 , A...
2024-09-02 | BIOMD0000000293 | BioModels
GenomicsGut bacterial aggregation study
Aggregation as a distinct phenotype in gut-associated bacteria from critically ill patients
PRJEB110522 | ENA
ModelsVazquez2014 - Chemical inhibition from amyloid protein aggregation kinetics
Vazquez2014 - Chemical inhibition from amyloid protein aggregation kinetics This model is described in the article: Modeling of chemical inhibition from amyloid protein aggregation kinetics. Vázquez JA. BMC Pharmacol Toxicol 2014; 15(1): 9 Abstract: BACKGROUNDS: The p...
2024-09-02 | BIOMD0000000532 | BioModels
ProteomicsNeuronal interactome changes upon aggregation of Tau
To understand at molecular level how aggregation of Tau modulates its interactions with proteins we reveal key determinant for derailing Tau protein network. By performing quantitative AP-MS we define a new set of interactors which bind Tau upon fibril formation. These interactors contain disordered...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-01-30 | PXD015432 | Pride
Fibrils Tau Molecular chaperones Protein aggregation Hsp90 Protein-protein interactions 
ModelsKuznetsov2016(II) - α-syn aggregation kinetics in Parkinson's Disease
Kuznetsov2016(II) - α-syn aggregation kinetics in Parkinson's This theoretical model uses 2-step Finke-Watzky (FW) kinetics todescribe the production, misfolding, aggregation, transport and degradation of α-syn that may lead to Parkinson's Disease (PD). Deregulated α-syn degradation is predicted t...
2024-09-02 | BIOMD0000000615 | BioModels
ModelsMorris2009 - α-Synuclein aggregation variable temperature and pH
Morris2009 - α-Synuclein aggregation variable temperature and pH This model is described in the article: Alpha-synuclein aggregation variable temperature and variable pH kinetic data: a re-analysis using the Finke-Watzky 2-step model of nucleation and autocatalytic growth. ...
2024-09-02 | BIOMD0000000566 | BioModels
UnknownEnzymatically catalyzed molecular aggregation.
Not available
S-EPMC11574095 | biostudies-literature
UnknownAge-Dependent Protein Aggregation Initiates Amyloid-β Aggregation.
Not available
S-EPMC5434662 | biostudies-literature
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