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ProteomicsCharacterization of the intratumoral heterogeneity using single cell-derived spheroids shows the involvement of metabolic changes during the metastatic cascade of colorectal cancer
Background: Colorectal cancer (CRC) stands as a significant contributor to cancer-related mortality globally. Approximately 90% of cancer mortality is due to distant metastasis. In the context of therapy, response rates can fluctuate significantly with approximately one-third of the patients experie...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD053393 | Pride
Intratumoral heterogeneity  single cells  spheroids  proteomics  aggresssiveness  metastatis  therapy resistance  intertumoral heterogeneity 
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