alarmone - OmicsDI

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Caulobacter vibrioides (4)
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Caulobacter vibrioides NA1000 (2)
Bacillus subtilis subsp. subtilis NCIB 3610 = ATCC 6051 = DSM 10 (2)
Bacillus subtilis subsp. subtilis str. 168 (2)
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Organisms

Caulobacter vibrioides (3)
Streptococcus mutans UA159 (3)
Pseudomonas aeruginosa PAO1 (3)
Bacillus subtilis subsp. subtilis NCIB 3610 = ATCC 6051 = DSM 10 (2)
Caulobacter vibrioides NA1000 (2)
Bacillus subtilis subsp. subtilis str. 168 (2)
Staphylococcus aureus (2)
Homo sapiens (2)
Brucella suis 1330 (1)
Rhizobium etli CFN 42 (1)
Pectobacterium atrosepticum SCRI1043 (1)
Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 (1)
Escherichia coli str. K-12 substr. MG1655 (1)
Bacteriophage sp. (1)
Pseudomonas putida (1)
Lactiplantibacillus plantarum (1)
Escherichia coli K-12 (1)
Arabidopsis thaliana (1)
Saccharomyces cerevisiae (1)

Repository

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geo (31)
biostudies-arrayexpress (15)
pride (10)
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Tissue

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Mass Spectrometry (10)
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Affinity purification coupled with mass spectrometry proteomics (2)
MSE (1)
SWATH MS (1)
Data-independent acquisition (1)
Bottom-up proteomics (1)
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Instrument Platform

Illumina HiSeq 2000 (2)
Illumina HiSeq 1500 (1)
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Liquid Chromatography MS - negative - reverse-phase (1)
Liquid Chromatography MS - positive - reverse phase (1)
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2014 (1)
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2006 (1)

CHEBI ID

CHEBI:17431 (1)
CHEBI:16238 (1)
CHEBI:15956 (1)
CHEBI:16750 (1)
CHEBI:18127 (1)

Metabolite Name

5-benzhydryl-1-(phenylsulfonyl)-1H-pyrazole (1)
3-(5-pyridin-3-yl-2-thienyl)prop-2-yn-1-ol (1)
2-[amino(3-chloroanilino)methylene]malononitrile (1)
10b-methyl-1,5,6,10b-tetrahydroimidazo[2,1-a]isoquinolin-2(3H)-one (1)
N1-(5-methylisoxazol-3-yl)-2-tetrahydro-1H-pyrrol-1-ylacetamide (1)
2-Styryl-1,3-benzoxazole (1)
4'-propyl[1,1'-biphenyl]-4-carboxamide (1)
1-Nitrosopyrrolidine (NPYR) (1)
¦Á-Hydroxyhippuric acid (1)
1-methyl-2-oxo-1,2-dihydroquinolin-4-yl N,N-dimethylcarbamate (1)
2-(4-methylphenyl)-2-oxoethyl thiocyanate (1)
4-methyl-6-[(4-methylphenyl)thio]-2-(2-pyridyl)pyrimidine (1)
3-(2,6-difluorophenyl)-4-ethyl-1H-pyrazole (1)
8-amino-5-hydroxy-4-iminonaphthalen-1-one (1)
4-fluoro-1,2-dihydro-3H-indazol-3-one (1)
4-methylpyridine-3-sulfonic acid (1)
7-chloro-4-[(5-propyl-2-pyrimidinyl)oxy]quinazoline (1)
3-(dimethylamino)-2-[3-(trifluoromethyl)phenyl]acrylonitrile (1)
2-(4-methylphenyl)imidazo[1,2-a]pyrimidine (1)
6,9-dimethoxy-11H-indeno[1,2-b]quinoxalin-11-one (1)
2-{[(2-hydroxy-1-naphthyl)methylidene]amino}isoindoline-1,3-dione (1)
1-allyl-4,5-diphenyl-2-(2-thienyl)-1H-imidazole (1)
2-methyl-1H-benzimidazole-5-carboxylic acid (1)
N1-bicyclo[2.2.2]oct-2-ylbenzamide (1)
N1-(2-cyanoethyl)-3-amino-4-chlorobenzene-1-sulfonamide (1)
3'-Dephospho-CoA (1)
2-[2-(2-pyridyloxy)ethoxy]pyridine (1)
Dihexylamine (1)
3-hydroxy-6-methoxy-2-phenyl-4H-chromen-4-one (1)
3-phenyl-5-[3-(trifluoromethyl)-1H-pyrazol-1-yl]-1,2,4-thiadiazole (1)

First Public Date

2014 (9)
2026 (7)
2023 (5)
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2019 (4)
2022 (3)
2020 (3)
2025 (2)
2024 (2)
2018 (2)
2017 (1)
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Classification

bacteria (12)
viruses (1)

Study type

Transcription profiling by array (11)
RNA-seq of coding RNA (2)
Transcription profiling by tiling array (1)
ChIP-seq (1)

Release Date

2020 (21)
2019 (20)
2018 (17)
2023 (15)
2016 (15)
2022 (13)
2021 (13)
2017 (13)
2025 (12)
2015 (12)
2024 (10)
2014 (6)
2013 (6)
2010 (6)
2012 (5)
2011 (5)
2008 (4)
2009 (2)
2007 (2)
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2005 (1)
2003 (1)

Lab affiliation

Department of Biological Sciences, Indian Institute of Science Education and Research (IISER), Kolkata, Mohanpur, District: Nadia, West Bengal, Pin Code: 741246, India (1)
Department of Molecular Biology Umeå University SE-901 87 Umeå Sweden (1)
1 Max-Planck Institute for Terrestrial Microbiology, Karl-von-Frisch Strasse 14, 35043 Marburg, Germany 2 University of Marburg, Center for Synthetic Microbiology (SYNMIKRO) & Departments of Chemistry and Biology, Karl-von-Frisch Strasse 14, 35043 Marburg, Germany (1)
Department of Chemistry University of Konstanz (1)
Max Planck Unit for the Science of Pathogens, Chariteplatz 1, 10117 Berlin, Germany (1)
Organic Chemistry / Cellular Chemistry, Dept. of Chemistry, University of Konstanz (Germany) (1)
Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, US (1)
Biochemistry and Structural Biology, Chemistry Department,Université Libre de Bruxelles, Belgium (1)
Functional Genomics Laboratory, Translational Health Science and Technology Institute, India (1)
University of Illinois at Chicago (1)

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The alarmone pGpp inhibits translation through GTP depletion I

PRJNA1425009 | ENA

The alarmone pGpp inhibits translation through GTP depletion II

PRJNA1425010 | ENA

Functional Characterization of Small Alarmone Synthetase and Small Alarmone Hydrolase Proteins from Treponema denticola.

Not available

S-EPMC10434055 | biostudies-literature

The alarmone pGpp inhibits translation through GTP depletion II

Bacteria produce the alarmone nucleotides ppGpp and pppGpp during stress to affect replication, transcription, and metabolism. ppGpp and pppGpp also attenuate translation by competitively binding translational GTPases to conserve resources during stress. Recently, pGpp was identified as a third alar...

ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168

2026-02-18 | GSE319727 | GEO

The alarmone pGpp inhibits translation through GTP depletion I

ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168

2026-02-18 | GSE319724 | GEO

Synthetase and Hydrolase Specificity Collectively Excludes 2'-Deoxyguanosine from Bacterial Alarmone.

Not available

S-EPMC10802352 | biostudies-literature

The alarmone (p)ppGpp is part of the heat shock response of Bacillus subtilis

Here, B. subtilis was used as a model organism to investigate how cells respond and adapt to proteotoxic stress conditions. Our experiments suggested that the stringent response, caused by raised levels of the (p)ppGpp alarmone, plays a role during thermotolerance development and the heat shock resp...

ORGANISM(S): Bacillus subtilis GB03

2020-03-09 | PXD015416 | Pride

Bacteria export alarmone synthetases that produce (p)ppApp and (p)ppGpp.

Not available

S-EPMC12691689 | biostudies-literature

Unique Features of Alarmone Metabolism in Clostridioides difficile.

Not available

S-EPMC9017329 | biostudies-literature

Functional Characterization of a Small Alarmone Hydrolase in Corynebacterium glutamicum.

Not available

S-EPMC5954133 | biostudies-literature

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