antibiotic resistance

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Unknown (22897)
Genomics (5451)
Transcriptomics (1137)
Proteomics (384)
Metabolomics (127)
Other (32)
Models (14)
Genomic (2)
Multiomics (2)

Organisms

Homo sapiens (315)
Mus musculus (154)
Staphylococcus aureus (87)
Escherichia coli (77)
Pseudomonas aeruginosa (55)
Streptomyces coelicolor (26)
Saccharomyces cerevisiae (23)
Caenorhabditis elegans (22)
Candida albicans (18)
Sus scrofa (18)
Acinetobacter baumannii (17)
Enterococcus faecalis (17)
Pseudomonas aeruginosa PAO1 (17)
Rattus norvegicus (15)
Arabidopsis thaliana (14)
Streptococcus pneumoniae (13)
Bacillus subtilis (12)
Mycobacterium tuberculosis (11)
Bos taurus (11)
Drosophila melanogaster (10)
Streptomyces coelicolor A3(2) (10)
Enterococcus faecium (10)
Campylobacter jejuni (9)
Burkholderia cenocepacia (8)
Salmonella enterica (8)
Bacillus subtilis subsp. subtilis str. 168 (7)
Mycobacterium tuberculosis H37Rv (6)
Corynebacterium glutamicum ATCC 13032 (5)
Danio rerio (5)
Streptomyces venezuelae (4)

Organisms

Escherichia coli (263)
Klebsiella pneumoniae (100)
Staphylococcus aureus (93)
Pseudomonas aeruginosa (86)
Acinetobacter baumannii (74)
Homo sapiens (46)
soil metagenome (42)
Mus musculus (42)
wastewater metagenome (39)
Pandoraea pneumonica (30)
Salmonella enterica (22)
Enterococcus faecalis (20)
Bacteria (20)
Escherichia coli K-12 (18)
46170 (18)
human gut metagenome (18)
Campylobacter coli (17)
Vibrio cholerae (16)
Escherichia coli str. K-12 substr. MG1655 (16)
activated sludge metagenome (16)
gut metagenome (16)
Enterococcus faecium (15)
Enterobacter hormaechei (14)
mouse gut metagenome (13)
Helicobacter pylori (11)
Campylobacter jejuni (11)
Enterobacter cloacae (10)
Pseudomonas aeruginosa PAO1 (10)
Neisseria gonorrhoeae (10)
aquatic metagenome (10)

Repository

ENA (5364)
biostudies-arrayexpress (921)
geo (333)
pride (258)
MetaboLights (95)
iProX (58)
MassIVE (53)
MetabolomicsWorkbench (22)
BioModels (13)
EGA (12)
GNPS (10)
jPOST (7)
PanoramaPublic (4)
dbGaP (2)
EVA (1)
FAIRDOMHub (1)
PAXDB (1)

Tissue

Cell culture (51)
Prokaryotic cell (6)
Permanent cell line cell (6)
Epithelial cell (6)
Cecum (5)
Liver (5)
Cell suspension culture (4)
Bacterial cells (3)
Blood (3)
Whole body (3)
Intestine (2)
Feces (2)
Urine (2)
Culture condition:anaerobically-grown cell (2)
Neutrophil (2)
Primary cell (2)
Monocyte (2)
Feces (2)
Macrophage (2)
Lung epithelium (1)
Biofilm (1)
CACO-2 cell (1)
Spore (1)
Quadriceps (1)
Bacterial protein (1)
Promastigote (1)
Seedling (1)
Melanocyte (1)
Bone marrow (1)
Leukocyte (1)

Disease

Antibiotic resistance (22)
Normal (4)
Breast cancer (2)
Gonorrhea (2)
Bacterial infectious disease (2)
Tuberculosis (2)
Colon cancer (2)
Primary acute lymphoblastic leukemia (1)
Pretreatment primary leukemia (1)
Chronic myelogenous leukemia (1)
B. dendrobatidis infection (1)
Hodgkin lymphoma, mixed cellularity, stage IV (1)
Infected (1)
Metarhizium anisopliae infected (1)
Melanoma (1)
T-cell acute lymphoblastic leukemia (1)
Euploid (1)
Obesity (1)
C. burnetii infected (1)
S enteritidis (1)
Control (1)
Congenital diarrhea (1)
Osteomyelitis (1)
Keratitis (1)
Leishmaniasis (1)
Recurrent urinary tract infections (1)
Sepsis (1)
Epidural abscess (1)
Hypersensitivity reaction type IV disease (1)
Drug allergy (1)

Technology Type

Mass Spectrometry (268)
Shotgun proteomics (145)
Mass spectrometry (63)
Bottom-up proteomics (52)
Data-dependent acquisition (38)
Mass spectrometry assay (28)
SWATH MS (18)
Data-independent acquisition (14)
NMR (12)
Top-down proteomics (11)
Gel-based experiment (10)
Affinity purification coupled with mass spectrometry proteomics (9)
EI (6)
Affinity proteomics (6)
HDMSE (5)
NMR spectroscopy (4)
ESI (4)
MSE (4)
SRM/MRM (4)
All-ion fragmentation (3)
Chemical cross-linking coupled with mass spectrometry proteomics (2)

Instrument Platform

NextSeq 500 (22)
Illumina NovaSeq 6000 (20)
Illumina HiSeq 2500 (17)
Illumina HiSeq 2000 (17)
Illumina HiSeq 4000 (10)
Illumina MiSeq (9)
Spectronic Helios Alpha UV-Vis spectrophotometer (5)
Ultracentrifuge (4)
ScanArray [PerkinElmer] (4)
Illumina NovaSeq X (4)
Illumina HiSeq 1500 (4)
ScanArray Lite [PerkinElmer] (3)
Bioanalyser (3)
NextSeq 2000 (3)
DNBSEQ-G400 (3)
Complete Genomics (2)
Anaerobic workstation with airlock (2)
GenePix Professional 4200A [Axon Instruments] (2)
Variable Atmosphere Incubator (2)
Scanning hardware (2)
NextSeq 550 (2)
Illumina DNA Prep sample preparation kits (Illumina Inc., San Diego, CA, USA). Final libraries concentrations and size were assessed with Quant-IT DNA Assay Kit and Agilent 4200 Tapestation System (Agilent Technologies, Milan, Italy), (1)
QIAamp DNA minikit, Qiagen, Germany (1)
HISAT2, TOPHAT2 (1)
BD FACS Melody, liquid handlers, centrifuge, thermo cycler (1)
High-performance computing workstation (1)
Protocol computer workstation running R statistical software (1)
Thermal cycler (PCR); Covaris ME220 focused ultrasonicator; magnetic separation rack; Agilent TapeStation system (D5000 and D1000 ScreenTape assays); Qubit fluorometer or equivalent; microcentrifuge. (1)
JANUS® G3 MDT automated liquid handling workstation (PerkinElmer); thermal cycler or incubator (42 °C); Zymo DNA Clean & Concentrator columns; AMPure XP magnetic bead purification system; magnetic separation rack. (1)
Multichannel pipettes or automated liquid handler; 384-well tissue culture plates; Class II biological safety cabinet; CO₂ incubator (37 °C, 5% CO₂). (1)

Publication Date

2010 (150)
2025 (136)
2012 (110)
2013 (109)
2024 (107)
2026 (103)
2014 (101)
2022 (96)
2023 (93)
2011 (93)
2021 (92)
2008 (88)
2015 (77)
2020 (70)
2016 (68)
2018 (56)
2019 (53)
2009 (50)
2007 (26)
2017 (23)
2005 (12)
2006 (6)
2004 (3)

UNIPROT ID/AC

CBP1_BACSU (1)
YHFQ_BACSU (1)
ILVA_BACSU (1)
COTA_BACSU (1)
SP0J_BACSU (1)
LEPU_BACSU (1)
YDZF_BACSU (1)
EX7L_BACSU (1)
GLXK_BACSU (1)
GUB_BACSU (1)
PSPA_BACSU (1)
YDBS_BACSU (1)
FLHP_BACSU (1)
LEPS_BACSU (1)
GLNH_BACSU (1)
YQGF_BACSU (1)
YKUM_BACSU (1)
YWCB_BACSU (1)
GGT_BACSU (1)
SBP_BACSU (1)
SUNT_BACSU (1)
PTEC_BACSU (1)
ALR1_BACSU (1)
COXX2_BACSU (1)
OPUBA_BACSU (1)
YFKK_BACSU (1)
YISP_BACSU (1)
YYAP_BACSU (1)
COTG_BACSU (1)
SDPI_BACSU (1)

CHEBI ID

CHEBI:33282 (1)
CHEBI:75989 (1)
CHEBI:71674 (1)
CHEBI:27667 (1)
CHEBI:61166 (1)
CHEBI:61931 (1)
CHEBI:57684 (1)
CHEBI:60374 (1)
CHEBI:57809 (1)
CHEBI:16037 (1)
CHEBI:2411 (1)
CHEBI:44245 (1)
CHEBI:64834 (1)
CHEBI:10965 (1)
CHEBI:17767 (1)
CHEBI:71673 (1)
CHEBI:58117 (1)
CHEBI:57508 (1)
CHEBI:60332 (1)
CHEBI:59648 (1)
CHEBI:16895 (1)
CHEBI:48942 (1)
CHEBI:62345 (1)
CHEBI:17897 (1)
CHEBI:58313 (1)
CHEBI:57510 (1)
CHEBI:58131 (1)
CHEBI:62213 (1)
CHEBI:48944 (1)
CHEBI:58897 (1)

Metabolite Name

Adenosine (29)
Uridine (27)
Adenine (26)
Succinic acid (23)
Uracil (22)
Guanosine (22)
L-Phenylalanine (21)
L-Proline (20)
L-Tyrosine (20)
Thymine (20)
Citric acid (20)
Hypoxanthine (19)
Inosine (19)
L-Tryptophan (18)
Cytosine (18)
Fumaric acid (18)
Palmitic acid (18)
Cytidine (18)
L-Threonine (17)
Ornithine (17)
Guanine (16)
Stearic acid (16)
Dodecanoic acid (16)
L-Histidine (15)
Xanthosine (15)
Betaine (15)
Benzoic acid (15)
Heptadecanoic acid (15)
L-Methionine (14)
L-Asparagine (14)

First Public Date

2025 (940)
2024 (886)
2026 (695)
2023 (490)
2022 (402)
2021 (396)
2020 (355)
2019 (279)
2018 (194)
2013 (192)
2017 (171)
2014 (145)
2016 (110)
2015 (98)
2012 (7)
2011 (4)

Modelling Approach

Constraint-based model (9)
Computational model (3)
Steady-state model (1)

Lab affiliation

Bioplatforms Australia (9)
Department of Clinical Microbiology, Sahlgrenska University Hospital, Gothenburg, Sweden (3)
Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, 75123, Uppsala, Sweden (3)
University of Greifswald, Institute of Microbiology, Department of Microbial Physiology and Molecular Biology (3)
Genomics Research Center, Academia Sinica, Taipei, 11529 Taiwan (3)
EDyP (3)
School of Biological and Behavioural Sciences Queen Mary University of London (2)
Department of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, DK-9220, Aalborg East, Denmark (2)
Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia. (2)
Lab. Neuro-oncologie en klinische en kanker proteomics Department of Neurology Erasmus MC (2)
Biozentrum, University of Basel, 4056 Basel, Switzerland (2)
Advanced Water Management Centre, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia (2)
Max Perutz Labs, Vienna, Austria (2)
Lanzhou University, Lanzhou, Gansu, China (2)
Jinan University (2)
Chemical and Biological Engineering, The Hong Kong University of Science and Technology (HKUST) (2)
Weizmann Institute of Science Department of Biomolecular Sciences Faculty of Biochemistry (1)
Erasmus MC, University Medical Center Rotterdam, Department of Neurology, Clinical and Cancer Proteomics (1)
Peter Lasch, Centre for Biological Threats and Special Pathogens, Proteomics and Spectroscopy (ZBS6), Berlin, Germany (1)
1. Department of Paediatrics, University Hospital of North Norway, Tromsø, Norway 2 Paediatric Research Group, Department of Clinical Medicine, Faculty of Health Sciences, UiT- The Arctic University of Norway, Tromsø, Norway. (1)
Laboratory of Antibiotic Resistance and Microbial Metabolomics, Kamenik & Balikova Novotna Lab, Institute of Microbiology of the Czech Academy of Sciences, Czech Republic (1)
Translational Research in Inflammation and Immunology Research Unit (TRIRU), Department of Mi-crobiology, Faculty of Medicine, Chulalongkorn University, 1873 Rama 4 Road, Pathumwan, Bangkok 10330, Thailand (1)
Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR 72205, USA Arkansas Children's Research Institute, 13 Children's Way, Little Rock, AR 72205, USA (1)
Baylor College of Medicine Department of Pathology and Immunology Texas Children's Microbioome Center Texas Children's Hospital 1102 Bates Ave Houston, TX 77030 USA (1)
University of Copenhagen Department of Veterinary and Animal Sciences Stigbøjlen 4 Frederiksberg C, Denmark (1)
Deparment of Molecular and Cellular Biology University of Guelph Guelph, Ontario, Canada Department of Proteomics and Signal Transduction Max Planck Institute of Biochemistry Martinsried, Germany (1)
Center for Tuberculosis Control of Guangdong Province, Guangzhou, 510630, China (1)
Robert Koch Institute, Centre for Biological Threats and Special Pathogens, Proteomics and Spectroscopy (ZBS6), Berlin, Germany (1)
Department of Physical Biochemistry, Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11 37077 Goetttingen (1)
Dr. Andreas Otto Institute for Microbiology Department of Microbial Proteomics Ernst-Moritz-Arndt-University Greifswald F.-L.-Jahn-Str. 15 17489 Greifswald phone: +49 3834 4205920 fax: +49 3834 4205902 (1)

IsPrivate

False (13)

Model Flag

Non Kinetic (4)

Submitter Keywords

Ersilia (3)
FAIR-AIML (3)
Machine Learning Model (3)
FROG (2)
Manuscript Accepted (1)

Classification

bacteria (1298)
viruses (6)
fungi (2)
protozoa (1)

Modification

3x(2)H labeled N6-acetyl-L-lysine (1)
57.02146 (1)
15.99491 (1)
Not available (1)
4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (603)
RNA-seq of coding RNA (96)
ChIP-seq (31)
Comparative genomic hybridization by array (21)
Other (19)
DNA-seq (18)
Unknown experiment type (14)
Transcription profiling by tiling array (14)
ChIP-chip by array (13)
RNA-seq of total RNA (11)
High-throughput sequencing (9)
RNA-seq of coding RNA from single cells (9)
ChIP-chip by tiling array (8)
Methylation profiling by array (8)
RNA-seq of non coding RNA (7)
Cell line - High-throughput sequencing (6)
Methylation profiling by high throughput sequencing (4)
Proteomic profiling by array (3)
Cell line - One-color microarray (2)
Transcription profiling by RT-PCR (2)
ATAC-seq (2)
Cell line - Methylation microarray (1)
Two-color microarray (1)
One-color microarray (1)
Human - High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
RNAi profiling by array (1)
Capture-C (1)
MicroRNA profiling by high throughput sequencing (1)
Bisulfite-seq (1)

Release Date

2025 (3118)
2022 (2827)
2023 (2723)
2024 (2519)
2021 (2371)
2020 (1889)
2019 (1490)
2018 (1210)
2017 (903)
2016 (798)
2015 (684)
2014 (567)
2013 (412)
2026 (401)
2012 (351)
2010 (300)
2011 (289)
2009 (195)
2008 (195)
2007 (118)
2005 (73)
2006 (71)
2003 (69)
2004 (52)
2002 (48)
1999 (40)
2001 (38)
2000 (38)
1998 (27)
1997 (1)

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Original data of bacterial antibiotic resistance lipidomics

Plasmid-mediated dissemination of mcr genes has severely compromised colistin efficacy, necessitating adjuvants that restore antibacterial potency without exacerbating toxicity. Despite their essential roles in bacterial survival and virulence, metal ion acquisition systems remain underexplored as t...

2026-08-13 | MTBLS15318 | MetaboLights

Cyromazine accelerates the dissemination of antibiotic resistance genes by promoting the conjugative transfer of the SXT integrative conjugative element

Antimicrobial resistance (AMR) is one of the most urgent challenges in public health, and the horizontal transfer of antibiotic resistance genes (ARGs) mediated by mobile genetic elements (MGEs) drives its widespread global dissemination. Although integrative conjugative elements (ICEs) outnumber...

2025-10-15 | MTBLS13146 | MetaboLights

A synthetic antibiotic class with a deeply-optimized design for overcoming bacterial resistance

The lack of new drugs that are effective against antibiotic-resistant bacteria has caused increasing concern in global public health. Based on this study, we report development of a modified antimicrobial drug through structure-based drug design (SBDD) and modular synthesis. The optimal modified ...

2024-07-03 | MTBLS10516 | MetaboLights

Omics and Computational Chemistry Reveal Environmental Residues of Anti-COVID-19 Drug Chloroquine Phosphate Drive Antibiotic Resistance Gene Dissemination

The widespread use of chloroquine phosphate (CQP) during the COVID-19 pandemic has led to its persistent residues in aquatic environments, yet its impact on the horizontal transfer of antibiotic resistance genes (ARGs) remains unknown. Herein, the effects and molecular mechanisms of CQP on plasmid-m...

2026-10-10 | MTBLS15990 | MetaboLights

Mechanisms of Iprovalicarb and Cycluron in Promoting Conjugative Transfer of Antibiotic Resistance Genes and Outer Membrane Vesicle-Mediated Dissemination

Detect pesticide residues in water, manure, and soil from waterfowl farms.

2026-08-07 | MTBLS15288 | MetaboLights

Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Escherichia coli assays)

The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (5 strains each) using an integrated application of genomic, transcriptomic, metabolomic and proteomic technologies. The pathogens included in this initiative are: Escheric...

2022-08-03 | MTBLS2015 | MetaboLights

Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Klebsiella pneumoniae assays)

2022-08-03 | MTBLS2322 | MetaboLights

Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Staphylococcus aureus assays)

2022-08-03 | MTBLS1898 | MetaboLights

Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pneumoniae assays)

2022-08-03 | MTBLS2323 | MetaboLights

Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pyogenes assays)

2022-08-03 | MTBLS2324 | MetaboLights