Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of mouse Podocytes reveal use of FcRn to clear IgG from the glomerular basement membrane
The glomerular filtration barrier prevents large serum proteins from being lost into the urine. It is not known, however, why the filter does not routinely clog with large proteins that enter the glomerular basement membrane (GBM). Here we provide evidence that an active transport mechanism exists t...
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-10017 | biostudies-arrayexpress
ProteomicsQuantitative Proteome Analysis Reveals Increased Content of Basement Membrane Proteins in Arteries from Patients with Type 2 Diabetes and Lower Levels among Metformin Users
We analyzed non-atherosclerotic repair arteries gathered at coronary by-pass operations from 30 patients with type 2 diabetes, as well as from 30 age- and gender-matched non-diabetic individuals. Quantitative proteome analysis was done by iTRAQ-labelling and LC-MS/MS analysis on individual arterial ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080848 | MassIVE
TranscriptomicsChanges in gene expression during acinar morphogenesis of normal-like human mammary epithelial cells in a 3D basement membrane cultures
In this study, we examined temporal changes in gene expression during acinar morphogenesis of normal-like human mammary epithelial cells (MCF-10A) in a three-dimensional (3D) basement membrane cultures. Changes in gene expression in 3D culture of MCF-10A cells were measured at 4, 8, and 12 days.
ORGANISM(S): Homo sapiens 
2013-12-01 | E-GEOD-33354 | biostudies-arrayexpress
TranscriptomicsEffects of a Tricaprylin Emulsion on Anti-glomerular Basement Membrane Glomerulonephritis in Rats
Expression data from rat with anti-glomerular basement membrane nephritis (anti-GBM). We used microarrays to analyze the transcriptome of kidney from anti-GBM model rat with or without drug treatment RNA from whole kidneys was extracted and processed for hybridization on Affymetrix microarrays.
ORGANISM(S): Rattus norvegicus 
2015-07-14 | E-GEOD-46295 | biostudies-arrayexpress
ProteomicsBasement Membranes from Human Retinal Blood Vessels, Inner Limiting Membranes, and Lens Capsules
Three types of BMs from adult human eyes, the inner limiting membrane, the retinal vascular BMs and the lens capsule, were isolated for analysis by 1D-SDS-PAGE and LC-MS/MS.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-29 | MSV000081772 | MassIVE
ProteomicsData in support of Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood-brain barrier
The aim of the present study was to analyze four different in vitro models of the murine BBB for expression and possible secretion of major basement membrane proteins from murine BCECs (mBCECs). The mBCECs and pericytes were isolated from brains of adult C57BL/6 mice, and glial cells (mainly astrocy...
ORGANISM(S): Mus musculus (Mouse) 
2016-08-03 | PXD003981 | Pride
Blood-brain barrier  primary murine capillary endothelial cells  basement membrane  in vitro models 
TranscriptomicsBasement membrane turnover and circulating matrix biomarkers in kidney disease
Chronic kidney disease (CKD) is characterised by kidney fibrosis and represents a major public health concern. Alport syndrome, a common monogenic cause of kidney failure caused by genetic variants in the type IV collagen genes COL4A3, COL4A4or COL4A5, leads to abnormal basement membrane remodelling...
ORGANISM(S): Mus musculus 
2026-05-27 | E-MTAB-15467 | biostudies-arrayexpress
OtherA proteomic view of basement membranes from human retinal blood vessels, inner limiting membranes, and lens capsules.
Data from ProteomeXchange, PXD ID: PXD001025. Experiment: ILM, file: ILM-2.mzml. Published as part of J Proteome Res. 2014 Jul 2 . From the Abstract: {{i}} Basement membranes (BMs) are extracellular matrix sheets comprising the laminins, type IV collagens, nidogens, and the heparan sulfate proteogl...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310002171 | GPMDB
Resource Reanalysis 
TranscriptomicsProteolytic inactivation of the autoinhibitory prodomain is essential for the pro-tumorigenic function of membrane type-1 matrix metalloproteinase (MT1-MMP)
Invasive cancers employ pericellular proteolysis to breach the extracellular matrix and basement membrane barriers and invade the surrounding tissue. Pro-invasive, pro-tumorigenic MT1-MMP is the primary mediator of proteolytic events on the cancer cell surface. Cellular MT1-MMP is synthesized as a l...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-28655 | biostudies-arrayexpress
GenomicsGene expression profile of a C. elegans Anchor cell invading through Basement Membrane
Gene expression profile of a C. elegans Anchor cell invading through Basement Membrane
PRJNA952249 | ENA
Sort   by:  
 Page size