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Morphology together with the capability to respond to surrounding stimuli are the key elements governing the spatial interaction of a living cell with the environment. In this respect, biomechanical stimulation can trigger significant physiological cascades that can potentially modulate or interact ...
ORGANISM(S): Homo sapiens (Human) 
2018-07-31 | PXD008996 | Pride
Background: Mechanical forces play a crucial role in regulating cellular communication during tissue repair, yet how mechanical stimulation modulates endothelial exosome secretion and their effects on fibroblast activation remains unclear. Methods: In this study, endothelial cells were incorporated ...
ORGANISM(S): Homo Sapiens 
2025-12-25 | PXD072415 |
Neonatal rat ventricular cardiomyocytes (NRVCMs) were stretched biaxially (112%/24h) or stimulated with phenylephrine (PE, 50 uM), both resulting in a similar degree of hypertrophy. Unstretched NRVCMs served as negative control. Affymetrix microarray analysis revealed 164 genes more than 2.0-fold up...
ORGANISM(S): Rattus norvegicus 
A global transcriptome profiling was performed by RNA-seq on human BM-MSCs exposed to biomechanical stimulation (perfusion) and biophysical stimulation (PEMF stimualtion) and the set of pathways and upstream regulators were detected using bioinformtic tools to determine how biophysical stimulation i...
ORGANISM(S): Homo sapiens 
2024-03-21 | GSE231791 | GEO
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