caloric restriction

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Metabolite Name

N1-Methyl-2-pyridone-5-carboxamide (3)
2-(3'-methylthio)propylmalate (2)
Glucose-6-glutamate (2)
Cycloheptyl (2)
L-Cysteine, N-acetyl-, ethyl ester (2)
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Isoamyl isothiocyanate (2)
Nor-psi-tropine (2)
4-Bis(2-hydroxyethyl)amino-L-phenylalanine (2)
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(S)-2-Acetamido-3-(4-chlorophenyl)propanoic acid (2)
N-Nervonoyl Asparagine (2)
6-Hydroxy-5-methoxy-1h-indole-2-carboxylic acid (2)
Octaethyleneglycol monododecyl ether (2)
17-Ethynyl-16-fluoroestradiol (2)
Daumone (2)
Homocysteine thiolactone (2)
2-(2-Butoxyethoxy)ethanol (2)
Arachidoyl Ethanolamide (2)
Hexanoyllysine (2)
S-(2-Carboxyethyl)-L-cysteine (2)
N-Myristoyl Arginine (2)
3-(6-Aminopurin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol (2)
L-Prolinamide, 5-oxo-L-prolyl-L-norvalyl- (2)

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Lab affiliation

Director of PEL @ Caltech (2)
1) Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany 2) CECAD, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany (1)
Assistant Professor of Medicine (Hematology) Senior Fellow, Duke Aging Center Duke Molecular Physiology Institute Duke University School of Medicine (1)
CECAD-Cluster of Excellence, University of Cologne, Joseph-Stelzmann-Str. 26, D-50931, Cologne, Germany; Department II of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, D-50937, Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Robert-Koch-Str. 21, D-50931, Cologne, Germany (1)
Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany CECAD, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany (1)
Department of Veterinary Medicine, University of Milan (1)
Director of PEL, CalTech (1)
Functional Phosphoproteomics lab, Murdoch Children's Research Institute, Melbourne Australia (1)
Huffington Center on Aging, Baylor College of Medicine, Houston, TX, United States (1)
IRCCS-Istituto Ricerche Farmacologiche Mario Negri (1)
Institute for Diabetes and Endocrinology (IDE) Helmholtz Zentrum München Ingolstaedter Landstr. 1 85764 Neuherberg, Germany (1)
Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Austria (1)
Instituto de Investigaciones Sanitarias de Santiago de Compostela (1)
Laboratory of Mass Spectrometry Institute of Bioorganic Chemistry Polish Academy of Sciences Poznan, Poland (1)
Markus Ralser, Prof. Dr. Einstein Professor of Biochemistry Head, Institute of Biochemistry, Charité University Medicine, Berlin markus.ralser@charite.de Senior Group Leader, The Francis Crick Institute, London markus.ralser@crick.ac.uk UK 0044 743 5315249 DE 0049 30 450528141 (1)
National Yang-Ming University, Proteomics Research Center, Taiwan (ROC) (1)
Obesity Research Unit, Research Program for clinical and Molecular Metabolism Faculty of Medicine, University of Helsinki, Helsinki, Finland eugene (1)
Porto Conte Ricerche (1)
Professor of Biochemistry and Molecular & Cellular Biology, Georgetown University, 3900 Reservoir Road, Washington, DC 20057 (1)
Team: Microenvironnement, Cancer and Adipocytes Institute of Pharmacology and Structural Biology BP64182 205 route de Narbonne 31077 Toulouse Cedex04 France (1)
Temple University School of Pharmacy, Philadelphia, PA,USA (1)
University Hospital Cologne (1)
University of Antwerp, Department of Veterinary Sciences, Laboratory of Veterinary Physiology and Biochemistry, Gamete Research Centre, Wilrijk, Belgium. (1)
University of Groningen, University Medical Center Groningen, Department of Cardiology, The Netherlands, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands (1)

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Nuclear Magnetic Resonance-Based Blood Metabolic Profiles of Rats Exposed to Short-Term Caloric Restriction

Caloric restriction increases life-span of a number of organisms. The relationship between the increase in life-span and the extent of caloric restriction, however, varies among species. The underlying mechanisms are yet unknown, but appear to be related to changes in metabolism. In order to investi...

2014-09-05 | MTBLS114 | MetaboLights

A high-fiber diet mimics aging-related signatures of caloric restriction in mammals

Caloric restriction (CR) delays aging-related hallmarks in various organisms by slowing growth and development while enhancing metabolic homeostasis. However, desirable diets that harness the metabolic benefits of CR without imposing food intake restrictions remain elusive. Here we evaluated the ...

2025-06-13 | MTBLS12479 | MetaboLights

Caloric Restriction vs drugs

Not available

ORGANISM(S): Mus musculus

ST000090 | MetabolomicsWorkbench

Prolonged fasting times reap greater geroprotective effects when combined with caloric restriction in adult female mice

Emerging new evidence highlights the importance of prolonged daily fasting periods for the health and survival benefits of calorie restriction (CR) and time-restricted feeding (TRF) in male mice; however, little is known about the impact of these feeding regimens in females. We placed 14-month-old f...

2024-05-14 | MTBLS790 | MetaboLights

Effects of caloric restriction in HCR/LCR rats

Not available

ORGANISM(S): Rattus norvegicus

ST000758 | MetabolomicsWorkbench

Transcription profiling of four mouse tissues following acute caloric restriction

Multi-tissue transcriptional response following acute caloric restriction in mice.

ORGANISM(S): Mus musculus

2007-05-17 | E-MEXP-748 | biostudies-arrayexpress

Amino Acid Quantifcation of obese patients on a 16 week caloric restriction from Plasma

Not available

ORGANISM(S): Homo sapiens

ST000483 | MetabolomicsWorkbench

D2 Glucose Quantifcation of obese patients on a 16 week caloric restriction from plasma

Not available

ORGANISM(S): Homo sapiens

ST000485 | MetabolomicsWorkbench

Amino Acid Quantifcation of obese patients on a 16 week caloric restriction from muscle biopsy

Not available

ORGANISM(S): Homo sapiens

ST000484 | MetabolomicsWorkbench

In vitro caloric restriction induces protective genes and functional rejuvenation in senescent SAMP8 astrocytes

Astrocytes are key cells in brain aging, helping neurons to undertake healthy aging or otherwise letting them enter into a spiral of neurodegeneration. We aimed to characterize astrocytes cultured from senescence-accelerated prone 8 (SAMP8) mice, a mouse model of brain pathological aging, along with...

ORGANISM(S): Mus musculus

2015-06-23 | E-GEOD-60388 | biostudies-arrayexpress

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