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GenomicsExome sequencing in patients with cardiac arrhythmias
The institut du thorax in Nantes (FR), the Academic Medical Center in Amsterdam (NL) and the University Hospital of Muenster (DE) have recruited 20 large families comprising at least 3 patients with cardiac arrhythmias and showing history of sudden cardiac death. For each family, the exome of one af...
EGAS00001000063 | EGA
TranscriptomicsThe AP-1 transcription factor Fosl-2 drives cardiac fibrosis and arrhythmias under immunofibrotic conditions
Fibrotic changes in the myocardium and cardiac arrhythmias represent fatal complications in rheumatic disease systemic sclerosis (SSc), however the underlying mechanisms remain elusive. Fos-related antigen-2 (Fosl-2) has been implicated in development of organ fibrosis. Mice overexpressing Fosl-2 (F...
ORGANISM(S): Mus musculus 
2022-10-27 | E-MTAB-12271 | biostudies-arrayexpress
GenomicsGenome-wide occupancy profile of Tbx3, Gata4, Nkx2-5 and p300 in adult mouse whole heart
The contraction pattern of the heart relies on the activation and conduction of the electrical impulse. Perturbations of cardiac conduction have been associated with congenital and acquired arrhythmias as well as cardiac arrest. The pattern of conduction depends on the regulation of heterogeneous ge...
ORGANISM(S): Mus musculus 
2012-06-22 | E-GEOD-35151 | biostudies-arrayexpress
GenomicsCardiac conduction system regeneration prevents arrhythmias after myocardial infarction
Cardiac conduction system regeneration prevents arrhythmias after myocardial infarction
PRJNA1030318 | ENA
GenomicsEGAS00001000063-sc-20110602 - samples
Exome sequencing in patients with cardiac arrhythmias
EGAD00001000022 | EGA
UnknownInfanticide vs. inherited cardiac arrhythmias.
Not available
S-EPMC7947592 | biostudies-literature
GenomicsInnervated human cardiac muscle model reveals sympathetic drivers of KCNH2-associated arrhythmias
Innervated human cardiac muscle model reveals sympathetic drivers of KCNH2-associated arrhythmias
PRJNA1378541 | ENA
GenomicsThe AP-1 transcription factor Fosl-2 drives cardiac fibrosis and arrhythmias under immunofibrotic conditions
The AP-1 transcription factor Fosl-2 drives cardiac fibrosis and arrhythmias under immunofibrotic conditions
PRJEB56761 | ENA
TranscriptomicsSensing Cardiac Electrical Activity with a Cardiomyocyte Targeted Optogenetic Voltage Indicator
Rationale: Monitoring and controlling cardiomyocyte activity with optogenetic tools offers exciting possibilities for fundamental and translational cardiovascular research. Genetically encoded voltage indicators may be particularly attractive for minimal invasive and repeated assessments of cardiac ...
ORGANISM(S): Mus musculus 
2015-09-02 | E-GEOD-69190 | biostudies-arrayexpress
UnknownStudy of genetic markers of cardiac arrhythmias in Kazakhstan.
Not available
S-EPMC5960908 | biostudies-literature
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