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CRISPR screen analysis of human cardiomyocyte polyploidization and CCNB1 expression
Analysis of effect of Cyclin B1 overexpression on differentiating hESCs at the gene expression level. The hypothesis tested in the present study was that Cyclin B1 overexpression prevents the exit from pluripotency in hESCs. Results provide important information on the effect of Cyclin B1 on hESCs, ...
ORGANISM(S): Homo sapiens 
Single-cell RNA sequencing of CCNB1+, polyploid, and diploid human iPSC-derived cardiomyocytes
SIN3A regulates porcine early embryonic development by modulating CCNB1 expression
Dihydroartemisinin suppresses the tumorigenesis and cycle progression of colorectal cancer by targeting CDK1/CCNB1/PLK1 signaling
We characterize genetic determinants of human cardiomyocyte polypolidization and CCNB1 insufficiency using pooled CRISPR screen methods
ORGANISM(S): Homo sapiens 
2021-05-04 | GSE147417 | GEO
We characterize transcriptional determinants and consequences of human cardiomyocyte polypolidization and CCNB1 insufficiency
ORGANISM(S): Homo sapiens 
2021-05-04 | GSE147249 | GEO
SIN3A is the central scaffold protein of the SIN3/HDAC transcriptional repressor complex. We previously found that SIN3A participates in the mouse preimplantation development by finetuning HDAC1 expression. However, it remains unresolved if this functional significance of SIN3A was conserved in othe...
ORGANISM(S): Sus scrofa 
2020-09-16 | GSE157650 | GEO
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