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ProteomicsThe Influences of ApoE Isoforms on Endothelial Adherens Junctions and Actin Cytoskeleton Responding to mCRP
Monomeric C-reactive protein (mCRP) plays a role in cerebrovascular damage mediated by apolipoprotein E4 (ApoE4) in Alzheimer's disease (AD) pathogenesis. Using proteomic profilings, we found altered cytoskeleton proteins in the microvasculature of AD brains, including increased levels of hyperphosp...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-05-06 | PXD051529 | Pride
Apolipoprotein e (apoe)  monomeric c-reactive protein (mcrp)  lim domain and actin binding 1 (lima1)  cd31 and pcd31  cerebrovascular  endothelia  f-actin  alzheimer’s disease (ad) 
UnknownMonomeric C-reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype-dependent pattern: A risk factor for Alzheimer's disease?
Not available
S-EPMC8590103 | biostudies-literature
UnknownThe influences of ApoE isoforms on endothelial adherens junctions and actin cytoskeleton responding to mCRP.
Not available
S-EPMC11564276 | biostudies-literature
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