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TranscriptomicsTranscriptomic analysis of chlorhexidine shock in Acinetobacter baumannii
In this study the transcriptomic changes occurring in A. baumannii ATCC 17978 in response to shock treament using the biocide chlorhexdine were determined. A. baumannii ATCC 17978 cells were grown at 37°C with shaking (200rpm) in 35mL cultures in MH broth to OD600=0.75, at which time they were spli...
ORGANISM(S): Acinetobacter baumannii 
2013-12-03 | E-GEOD-51525 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Pseudomonas aeruginosa to investigate the toxicogenomic Effects of Chlorhexidine diacetate
In the present study, we employed Affymetrix Pseudomonas aeruginosa GeneChip arrays to investigate the dynamics of global gene expression profiles during the cellular response of Pseudomonas aeruginosa to Chlorhexidine diacetate, which involved initial growth inhibition and metabolism. Experiment Ov...
ORGANISM(S): Pseudomonas aeruginosa 
2009-01-17 | E-GEOD-14253 | biostudies-arrayexpress
TranscriptomicsTranscriptomic comparison of chlorhexidine tolerant and sensitive Salmonella Typhimurium
Transcriptional profiles of a chlorhexidine tolerant Salmonella Typhimurium were compared to its, chlorhexidine sensitive, isogenic progenitor isolate. RNA was extracted from mid-log phase cells from both isolates, without chlorhexidine exposure and following exposure to 1 µg/ ml of chlorhexidine fo...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2015-06-06 | E-GEOD-59566 | biostudies-arrayexpress
TranscriptomicsTranscriptomics analysis of E. faecalis V583 exposed to subinhibitory concentration of chlorhexidine
The vancomycin resistant strain V583 was exposed to subinhibitory concentration of chlorhexidine. E. faecalis V583 cells were collected at 15 minutes after chlorhexidine addition and without chlorhexidine, for RNA extraction and hybridization on Affymetrix microarrays.
ORGANISM(S): Enterococcus faecalis V583 
2017-01-11 | E-MTAB-5181 | biostudies-arrayexpress
TranscriptomicsM-TraM analysis for identification of chlorhexidine resistance genes in Enterococcus faecium E1162
Microarray-based Transposon Mapping (M-TraM) of E. faecium E1162 to identify conditionally essential genes, required for growth in the presence of chlorhexidine (1.2 ug/ml)
ORGANISM(S): Enterococcus faecium 
2016-07-03 | E-MTAB-4173 | biostudies-arrayexpress
TranscriptomicsResponse of Burkholderia cenocepacia J2315 to subinhibitory concentration of chlorhexidine
Burkholderia cenocepacia J2315 was grown in LB broth with and without the presence of the desinfectant chlorhexidine in the subinhibitory concentration of 5mg/L. Four biological replicates for each control and test conditions were performed. The experiment was designed as a direct comparison with dy...
ORGANISM(S): Burkholderia cenocepacia 
2012-05-10 | E-MEXP-3207 | biostudies-arrayexpress
ProteomicsChlorhexidine promotes psl in Pseudomonas aeruginosa that enhances cell aggregation with preserved pathogenicity demonstrates an adaptation against antiseptic
Because Pseudomonas aeruginosa is a common pathogen that frequently contacts with Chlorhexidine digluconate (a regular antiseptic), then adaptations against Chlorhexidine were tested. In com-parison with the parent strain, the Chlorhexidine-adapted strain formed smaller colonies with the downregulat...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD034530 | Pride
Pseudomonas aeruginosa  chlorhexidine digluconate  chlorhexidine  cross-resistance  biofilm  psl  cell aggregate  persistence  wound infection 
TranscriptomicsTranscription profiling of Burkholderia cenocepacia J2315 sessile cells to treatment with high doses of hydrogen peroxide, sodium hypochlorite and chlorhexidine
In order to unravel the molecular mechanisms involved in the resistance of biofilm-grown
Burkholderia cenocepacia cells against high concentrations of disinfectants, the present
study focussed on the transcriptional response in sessile B. cenocepacia J2315 cells
following exposure to hig...
ORGANISM(S): Burkholderia cepacia 
2010-03-02 | E-MEXP-2502 | biostudies-arrayexpress
TranscriptomicsTranscriptomic comparison of chlorhexidine tolerant and sensitive Salmonella Typhimurium
Transcriptional profiles of a chlorhexidine tolerant Salmonella Typhimurium were compared to its, chlorhexidine sensitive, isogenic progenitor isolate. RNA was extracted from mid-log phase cells from both isolates, without chlorhexidine exposure and following exposure to 1 µg/ ml of chlorhexidine fo...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2015-06-06 | GSE59566 | GEO
GenomicsSalivary Microbiota and Antimicrobial Resistance in Relation to Chlorhexidine Use
0.06% Chlorhexidine and salivary microbiota study
PRJEB108494 | ENA
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