Sort   by:  
 Page size 
MetabolomicsMetabolomic Responses to Circadian Rhythm Disruption in Zebrafish

Circadian rhythms are essential biological oscillators that synchronize physiological processes, cellular homeostasis, and systemic metabolism with the Earth's natural 24-hour light-dark cycle. While circadian rhythm disruption (CRD) is highly prevalent in modern society due to factors such as sh...

2026-06-23 | MTBLS14815 | MetaboLights
MetabolomicsInvestigating the effects of circadian rhythm on the human skin lipidome

The circadian rhythm is a 24 h cycle that harmonises the activity of organs – including the skin – to a daily routine using neurological and hormonal signals. Limited research has been done to understand the effects of the circadian rhythm on the skin lipidome. We used reverse...

2025-10-17 | MTBLS12607 | MetaboLights
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS382 | MetaboLights
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS380 | MetaboLights
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS390 | MetaboLights
MetabolomicsThe microbiome interacts with the circadian clock and dietary composition to regulate metabolite cycling in the gut
Gut microbiomes play a key role in the maintenance of host metabolic homeostasis and health. An important aspect of metabolism is its circadian regulation, but how the microbiome regulates metabolite cycling under different conditions, including variations in dietary composition, remains undefined. ...
2025-04-08 | MTBLS8819 | MetaboLights
MetabolomicsCircadian disruption exacerbates MASH in mice by reducing intestinal Akkermansia muciniphila abundance via the FXR-CYP7A1-bile acid axis_Targeting Bile Acids_Untargeted Serum Metabolomics

Circadian disruption has emerged as a significant public health issue and is increasingly recognized as a contributor to the progression of metabolic dysfunction-associated steatotic liver disease (MASLD), though the underlying mechanisms remain poorly understood. In this study, we established a ...

2026-02-05 | MTBLS13848 | MetaboLights
ProteomicsCyanobacterial circadian regulation enhances bioproduction under subjective nighttime through rewiring of carbon partitioning dynamics, redox balance orchestration, and cell cycle modulation
GC-MS extracellular metabolite profiling of circadian clock regulation impacts of carbon partitioning between storage, growth, and product synthesis in Synechococcus elongatus PCC 7942 for enhanced bioproduction strategy investigation. Metabolomic targeted analysis of PCC 7942 light-dark cycle cultu...
ORGANISM(S): Synechococcus Elongatus Pcc 7942 (ncbitaxon:1140) 
2024-12-21 | MSV000096722 | MassIVE
Transcriptomicstranscriptional analysis of breast circadian clock
Circadian clocks drive ~24 hr rhythms in tissue physiology. They rely on transcriptional/translational feedback loops driven by interacting networks of clock complexes.To gain insights into the role of the mammary clock, circadian time-series microarrays were performed to identify rhythmic genes in ...
ORGANISM(S): Mus musculus 
2017-12-01 | E-MTAB-5330 | biostudies-arrayexpress
TranscriptomicsSIRT6 and SIRT1 contribute to circadian gene expression
Comparison of the hepatic circadian transcriptomes reveals that SIRT6 and SIRT1 separately control transcriptional specificity, and therefore, define distinctly partitioned classes of circadian genes. Livers from WT and SIRT6 KO mice, and livers from WT and SIRT1 KO mice, were harvested over the cir...
ORGANISM(S): Mus musculus 
2014-08-05 | E-GEOD-57830 | biostudies-arrayexpress
Sort   by:  
 Page size