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ProteomicsPhenotypic Proteomic Profiling Reveals Convergent Kinase Targets for Circadian Clock Modulators
Determining the mechanisms of action of drug molecules that modulate circadian rhythms is critical to develop novel compounds to treat clock disorders. Here we employed Phenotypic Proteomic Profiling (PPP) integrating multipronged proteomics approaches including global proteome, phosphoproteome, kin...
ORGANISM(S): Homo sapiens (Human) 
2019-11-25 | PXD014186 | Pride
Circadian rhythms  circadian period altering compounds  kinase  phenotypic proteome profiling  phosphoproteome  proteomics  thermal proteome profiling 
UnknownModulatory effects of cinnamomi cortex and its components epicatechin and linalool on skin circadian rhythms.
Not available
S-EPMC11803083 | biostudies-literature
TranscriptomicsChIP-chip from H9 hESCs for RNA Polymerase II, TBP, TAF3, TAF5, TAF7, and TAF11
The general transcription factor TFIID is composed of the TATA-box-binding protein (TBP) and approximately 14 TBP-associated factors (TAFs). Here we find, unexpectedly, that undifferentiated human embryonic stem cells (hESCs) contain only six TAFs (TAFs 2, 3, 5, 6, 7 and 11), whereas following diffe...
ORGANISM(S): Homo sapiens 
2012-11-19 | E-GEOD-39312 | biostudies-arrayexpress
TranscriptomicsPHF3 binds RNA polymerase II via the SPOC domain and regulates transcription of neuronal genes - PROseq
PRO-seq data of WT, KO, and dSPOC HEK293 cells.
ORGANISM(S): Homo sapiens 
2021-09-07 | E-MTAB-7501 | biostudies-arrayexpress
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