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By combining in vitro COPI vesicle reconstitutions and SILAC-based mass spectrometric analysis this study aims to identify the core proteome of mammalian COPI vesicles. Furthermore proteomes generated from vesicles with γ- and ζ-COP as well as Arf isoforms have been investigated with the same approa...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-02-23 | PXD012129 | Pride
To investigate whether some COPI vesicles contain LEPROTs and whether LEPROT-enriched vesicles carry specific clients
ORGANISM(S): Homo Sapiens 
2024-11-12 | PXD057776 |
Distinct roles of COPI proteins attenuated with cell senescence
Cellular senescence is characterized by persistent cell cycle arrest, apoptosis resistance, and widespread changes in gene expression. Although the functional alterations in organelles like mitochondria and lysosomes are well characterized, senescence-associated changes in the structure and function...
ORGANISM(S): Homo sapiens 
2026-06-11 | GSE302417 | GEO
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